gap junction

noun

: an area of contact between adjacent cells characterized by modification of the plasma membranes for intercellular communication or transfer of low molecular-weight substances

Examples of gap junction in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
When the researchers blocked the tumor cells’ ability to build the straw-like structures, officially known as gap junctions, the tumors stopped growing. Linda Carroll, NBC news, 20 Aug. 2025 Frank Winkler has started a glioblastoma trial targeting neurotransmitter receptors and gap junctions that are involved in signaling between neurons and cancer cells. Ingrid Wickelgren, Scientific American, 14 Feb. 2025 Cells have other options for exchanging molecules, most notably the structures called gap junctions and exosomes. Quanta Magazine, 23 Apr. 2018

Word History

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of gap junction was in 1967

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Cite this Entry

“Gap junction.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gap%20junction. Accessed 10 Sep. 2025.

Medical Definition

gap junction

noun
: an area of contact between adjacent cells characterized by modification of the plasma membranes for intercellular communication or transfer of low molecular-weight substances
gap-junctional adjective

More from Merriam-Webster on gap junction

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