Definition of ganglioside
: any of a group of glycolipids that yield a hexose sugar on hydrolysis and are found especially in the plasma membrane of cells of the gray matter
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A mutation in the GLB1 gene causes the disease by not producing an enzyme that breaks down a substance known as GM1 ganglioside, which eventually reaches toxic levels.
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Medical Dictionary
medical Definition of ganglioside
: any of a group of glycolipids that are found especially in the plasma membrane of cells of the gray matter and have sialic acid, hexoses, and hexosamines in the carbohydrate part and ceramide as the lipid
Learn More about ganglioside
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Britannica.com: Encyclopedia article about ganglioside
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