ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

ˈser-

plural ceramides

: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids

The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.

—L. Stivitz

Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.

—Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web

Whether your hair has been fried from hot tools or color treatments, this treatment coats every strand using ceramides and collagen. —Sarah Han, Allure, 9 Oct. 2025

Meanwhile, ceramides add extra hydration . —Conçetta Ciarlo, Vogue, 8 Oct. 2025

It was developed alongside dermatologists and features hyaluronic acid and ceramides for all-day (and all-night) hydration. —Stephanie Osmanski, Better Homes & Gardens, 6 Oct. 2025

Packed with anti-aging ingredients, actives, and ceramides, they’re built to target issues and deliver serious results. —Essence, 30 Sep. 2025

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Rhymes for ceramide

• actinide
• aldehyde
• alkoxide
• alongside
• amplified
• arsenide
• beautified
• biocide
• butoxide
• calcified
• certified
• citywide

Medical Definition

ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue