ceramide

noun

cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.L. Stivitz
Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web
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Buffering with a ceramide-rich moisturizer reduces redness and peeling during the first weeks of use. Allison Palmer updated June 13, Fort Worth Star-Telegram, 13 June 2026 The CeraVe formula is also packed with ceramides, another ingredient Hall recommends to incorporate when using strong actives to protect and strengthen the skin barrier, as well as hyaluronic acid to draw moisture into the skin. Maggie Horton, PEOPLE, 12 June 2026 The new product is made with the signature glazing milk formula and includes skin-friendly ingredients such as a ceramide trio, vitamin E and glycerin, according to Rhode. Saman Shafiq, USA Today, 8 June 2026 Night creams with barrier-repairing staples—think ceramides and hyaluronic acid—are also key. Jenny Berg, InStyle, 4 June 2026 See All Example Sentences for ceramide

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ceramide was in 1958

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Cite this Entry

“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 17 Jun. 2026.

Medical Definition

ceramide

noun
cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue

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