ceramide

noun

cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.L. Stivitz
Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web
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Boosting moisture and strengthening your skin’s barrier without ever turning oily, it’s created with a powerhouse blend of ceramides, AHAs and youth-boosting nutrients loved by makeup artists and skin care lovers. Tory Johnson, ABC News, 2 Mar. 2026 Infused with a blend of five ceramides and two forms of peptides, the formula is exceptionally hydrating—boasting a high-shine finish that looks identical to a glassy lip gloss. Kiana Murden, Vogue, 2 Mar. 2026 Collagen and ceramides, staples in Korean skin care, show up here to support hair that’s feeling weak, dry, or overworked. Christa Joanna Lee, Allure, 26 Feb. 2026 Ingredients commonly recommended for mature skin include ceramides, hyaluronic acid, glycerin and shea butter or similar emollients. Allison Palmer updated February 25, Miami Herald, 25 Feb. 2026 See All Example Sentences for ceramide

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ceramide was in 1958

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Cite this Entry

“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 6 Mar. 2026.

Medical Definition

ceramide

noun
cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue

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