ceramide

noun

cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.L. Stivitz
Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Rosemary oil—one of the key ingredients in the mask—is like hair-growth gold, but ceramides, jojoba, and keratin are also present in the strengthening and thickening formula. Kaitlin Clapinski, InStyle, 10 Feb. 2026 Enriched with skin-barrier-boosting ingredients like ceramides, hyaluronic acid, and natural butters, the blush reflects the brand’s skincare-first philosophy. Jenny Berg, Vogue, 9 Feb. 2026 This ultrafine spray delivers ceramides and a lipid complex—a mix of ceramides, fatty acids, and cholesterol that mimic your skin’s natural lipids—to calm skin, lock in moisture, and strengthen the barrier. Lily Wohlner, Allure, 1 Feb. 2026 With a combination of ceramides, hyaluronic acid, and niacinamide, the CeraVe Eye Repair Cream’s hydrating formula is designed to depuff and reduce dark circles while leaving your eyes feeling refreshed and awake. Caley Sturgill, Southern Living, 24 Jan. 2026 See All Example Sentences for ceramide

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ceramide was in 1958

Browse Nearby Words

Cite this Entry

“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 14 Feb. 2026.

Medical Definition

ceramide

noun
cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue

More from Merriam-Webster on ceramide

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster