noun epi·ge·nome \ˌe-pə-ˈjē-ˌnōm\

Definition of epigenome

  1. :  the complement of chemical compounds that modify the expression and function of the genome Access to the genes is controlled by the epigenome, a layer of millions of proteins and other marks that attach themselves to the genome. — Nicholas Wade Working out which genes are switched on or not involves looking at the epigenome, or the chemical “methyl” tags attached to genes. — New Scientist

Origin and Etymology of epigenome

epi- + genome, after epigenetic

First Known Use: 1991

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