epigenetic

adjective

epi·​ge·​net·​ic ˌe-pə-jə-ˈne-tik How to pronounce epigenetic (audio)
1
a
: of, relating to, or produced by the chain of developmental processes in epigenesis that lead from genotype to phenotype after the initial action of the genes
b
: relating to, being, or involving changes in gene function that do not involve changes in DNA sequence
epigenetic inheritance
2
of a deposit or structure : formed after the laying down of the enclosing rock
epigenetically adverb

Examples of epigenetic in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Advertisement My lab has focused mostly on epigenetic regulation [which is the process by which genes can be turned on or off by certain biochemical mechanisms]. Dominique Mosbergen, Time, 16 Oct. 2025 Further analysis revealed that SARS-CoV-2 infection had altered small noncoding RNA molecules (sncRNAs) in sperm – epigenetic markers known to influence how genes are expressed in the next generation. New Atlas, 13 Oct. 2025 Environmental and epigenetic factors also play significant roles. Suchandrima Bhowmik, Health, 12 Oct. 2025 Evelyn’s agenda, articulated in a book that is unconvincingly treated as a bestseller, has something to do with epigenetic trauma and kids being the victims of psychoses patterned through their parents. Daniel Fienberg, HollywoodReporter, 24 Sep. 2025 See All Example Sentences for epigenetic

Word History

Etymology

epi- + genetic, after epigenesis

First Known Use

1883, in the meaning defined at sense 1a

Time Traveler
The first known use of epigenetic was in 1883

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Cite this Entry

“Epigenetic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/epigenetic. Accessed 24 Oct. 2025.

Medical Definition

epigenetic

adjective
epi·​ge·​net·​ic -jə-ˈnet-ik How to pronounce epigenetic (audio)
1
: of, relating to, or produced by epigenesis
the epigenetic nature of vertebrate development
2
: relating to, being, or involving a modification in gene expression that is independent of the DNA sequence of a gene
epigenetic carcinogenesis
epigenetic inheritance
Methylation is one of many epigenetic signals—chemical changes to DNA and its associated proteins—that modify gene activity without altering the genetic information itself.Tina Hesman Saey, Science News
epigenetically adverb
Last Updated: - Updated example sentences
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