dependence

noun

de·​pen·​dence di-ˈpen-dən(t)s 

variants or less commonly dependance

1

: the quality or state of being dependent

especially : the quality or state of being influenced or determined by or subject to another

2

: reliance, trust

3

: one that is relied on

4

a

: drug addiction

developed a dependence on painkillers

b

: habituation sense 2b

Synonyms of dependence

• dependency
• reliance

Examples of dependence in a Sentence

The company was hurt by its dependence on government loans.

Our dependence upon foreign oil makes our economy vulnerable.

a harmful dependence on foreign oil

Recent Examples on the Web

Bolstering the state’s dependence on fossil fuels forces us to keep funding the destruction of our environment, health, and a civil democratic society. —Anshul Gupta, New York Daily News, 7 Jan. 2026

The prescription opioid pill, called naltrexone, was first approved by the FDA to treat opioid dependence in 1984. —Melissa Rudy, FOXNews.com, 7 Jan. 2026

Lembke pointed to rising dependence on digital media and a subset of Gen Z that rarely leaves home. —Jason Mastrodonato, Mercury News, 6 Jan. 2026

Before dying of cancer in 2013, Chávez handpicked Maduro as his successor, entrusting him with a country already buckling under the weight of dependence on oil, and the realization that prosperity was coming to an end. —Jorge Valencia, NPR, 5 Jan. 2026

Word History

Etymology

Middle English dependaunce, borrowed from Anglo-French dependence, dependance, from dependant dependent entry 1 + -ence, -ance -ence, -ance

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing dependence

• linear dependence
• self-dependence

Rhymes for dependence

• ascendance
• attendance
• dependance
• transcendence
• interdependence
• superintendence
• tendance

Kids Definition

dependence

noun

de·​pend·​ence

di-ˈpen-dən(t)s

1

: the quality or state of being dependent

especially : the quality or state of being influenced by or subject to another

2

: reliance sense 2, trust

3

: something on which one relies

4

: a drug addiction

Medical Definition

dependence

noun

de·​pen·​dence di-ˈpen-dən(t)s 

1

: the quality or state of being dependent upon or unduly subject to the influence of another

2

a

: drug addiction

b

: habituation sense 2b