de novo

adverb or adjective
de no·​vo | \ di-ˈnō-(ˌ)vō How to pronounce de novo (audio) , dā-, dē- \

Definition of de novo

: over again : anew a case tried de novo

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Synonyms & Antonyms for de novo



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Examples of de novo in a Sentence

Recent Examples on the Web At this moment, the helpful types of de novo proteins are attracting an increasing amount of scientific energy and expertise, and the molecules may be coming to a clinic near you. Rowan Jacobsen, Scientific American, 27 June 2021 If not, what are these giants doing to make that de novo certificate meaningful at the top of the hiring funnel? Ryan Craig, Forbes, 11 June 2021 Parts of data highways have been built by cloud platform and AI analytics providers embracing data-centric business models based on de novo design of scalable, user- and vendor-agnostic architectures. Stefan Harrer, Forbes, 1 June 2021 Later, at a big hospital in Columbus, an oncologist diagnosed me with metastatic breast cancer de novo. Tori Geib As Told To Zee Krstic, Good Housekeeping, 16 Dec. 2020 Rosetta contained a precise model of the spike; Cao had written scripts that used that model to generate, de novo, binders that might work. Matthew Hutson, The New Yorker, 18 Sep. 2020 Akili is seeking authorization to market its game under the de novo pathway — meant for relatively safe medical devices and software without precedent. Rebecca Robbins, STAT, 22 Apr. 2020 Yet, in a strict sense, nothing in evolution is created de novo. Quanta Magazine, 9 Apr. 2020 That confirmed that the de novo mutations were indeed playing some role in contributing to autism. Alice Park, Time, 23 Dec. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'de novo.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of de novo

1536, in the meaning defined above

History and Etymology for de novo


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Time Traveler for de novo

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The first known use of de novo was in 1536

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Last Updated

1 Jul 2021

Cite this Entry

“De novo.” Dictionary, Merriam-Webster, Accessed 30 Jul. 2021.

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More Definitions for de novo

de novo

adverb or adjective
de no·​vo | \ dē-ˈnō-vō, dā- How to pronounce de novo (audio) \

Legal Definition of de novo

: over again : as if for the first time: as
a : allowing independent appellate determination of issues (as of fact or law) a de novo review
b : allowing complete retrial upon new evidence — compare abuse of discretion, clearly erroneous

Note: A de novo review is an in-depth review. Decisions of federal administrative agencies are generally subject to de novo review in the U.S. District Courts, and some lower state court decisions are subject to de novo review at the next level.

History and Etymology for de novo

Medieval Latin, literally, from (the) new


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