cyclosporine

noun

cy·clo·spor·ine | \ ˌsī-klə-ˈspȯr-ən

, -ˌēn\

variants: or less commonly cyclosporin \ ˌsī-klə-ˈspȯr-ən

Definition of cyclosporine

: an immunosuppressive drug C₆₂H₁₁₁N₁₁O₁₂ that is a cyclic polypeptide obtained as a metabolite from a fungus (Beauveria nivea synonym Tolypocladium inflatum) and is used especially to prevent rejection of transplanted organs and in the treatment of rheumatoid arthritis and psoriasis

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Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. — Vogue, "Danish Jewelry Designer Vibe Harsløf’s Riffs on the Omnipresent EarPod are Something to Shout About," 23 Aug. 2019 Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. — Vogue, "Danish Jewelry Designer Vibe Harsløf’s Riffs on the Omnipresent EarPod are Something to Shout About," 23 Aug. 2019 Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. — Vogue, "Danish Jewelry Designer Vibe Harsløf’s Riffs on the Omnipresent EarPod are Something to Shout About," 23 Aug. 2019 Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. — Vogue, "Danish Jewelry Designer Vibe Harsløf’s Riffs on the Omnipresent EarPod are Something to Shout About," 23 Aug. 2019 Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. — Vogue, "Rosalía Just Kickstarted Festival Season’s Unlikeliest Trend," 8 July 2019 Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. — Vogue, "Rosalía Just Kickstarted Festival Season’s Unlikeliest Trend," 8 July 2019 Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. — Vogue, "Rosalía Just Kickstarted Festival Season’s Unlikeliest Trend," 8 July 2019 Are or may be pregnant, have osteoporosis, have severe liver disease, or take medicines known as strong OATP1B1 inhibitors, such as cyclosporine or gemfibrozil. — Glamour, "The Biggest Swimwear Color Trends for Summer 2019," 25 May 2019

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17 Oct 2019

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The first known use of cyclosporine was in 1976

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More Definitions for cyclosporine

cyclosporine

noun

cy·clo·spor·ine | \ ˌsī-klə-ˈspȯr-ᵊn, -ˌēn

variants: also cyclosporin \ ˌsī-klə-ˈspȯr-ᵊn \ or cyclosporine A or cyclosporin A or chiefly British ciclosporin or ciclosporin A

Medical Definition of cyclosporine

: a cyclosporin C₆₂H₁₁₁N₁₁O₁₂ that is an immunosuppressive cyclic polypeptide obtained as a metabolite from a fungus (Beauveria nivea synonym Tolypocladium inflatum) and is used especially to prevent rejection of transplanted organs and in the treatment of rheumatoid arthritis and psoriasis The indications for treatment with cyclosporine are rapidly expanding. Once used only for the prevention of organ transplant rejection, cyclosporine is now approved for psoriasis and rheumatoid arthritis and is being prescribed for conditions ranging from autoimmune diseases to atopic dermatitis.— Mark Lebwohl, Scientitic American Medicine Bulletin, February 2000 Recently, cyclosporine has come on the market as an especially useful immunosuppressive agent, since it offers essentially equal protection from rejection of the transplant, while causing less impairment of immunological defenses against bacteria and viruses.— James D. Hardy, The World of Surgery, 1986 Cyclosporin, an antirejection drug that helps make organ transplants feasible, comes from a Norwegian fungus.— Jon R. Luoma, Audubon, March 1996 Prolonged treatment with glucocorticoids can have undesirable side effects (including diabetes mellitus), while cyclosporine A can cause diarrhea and vomiting (and diminished bank accounts for owners of large dogs). — Dog Watch, July 2007

Note: Trademarks for cyclosporine include Neoral, Restasis, and Sandimmune.