: a white crystalline nitrogenous substance C4H9N3O2 found especially in the muscles of vertebrates either free or as phosphocreatine
also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Ingredients such as creatine and beta-alanine generally work through consistent use over time, not by getting into your system as quickly as possible. Dr. Onaola Adedeji, ABC News, 13 Aug. 2026 Some experts recommend loading up on creatine initially by taking 20 grams split throughout the day for 5-7 days. Isabel Vasquez Rd Ldn, Health, 30 July 2026 Second, fueling the cellular engine with proper nutrition, like complex carbs, and considering supplements like creatine, alongside hormonal rhythms. Luciana Paulise, Forbes.com, 23 July 2026 Research suggests creatine may help support healthy aging by preserving muscle function when paired with regular exercise. Sara Hoffman, Verywell Health, 20 July 2026 See All Example Sentences for creatine

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Time Traveler
The first known use of creatine was in 1840

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Cite this Entry

“Creatine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/creatine. Accessed 17 Aug. 2026.

Medical Definition

: a white crystalline nitrogenous substance C4H9N3O2 found especially in vertebrate muscle either free or as phosphocreatine

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