creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Some data suggest that multivitamins, vitamin D, and omega-3 or fish oil supplements can help fill nutrient gaps while taking GLP-1s, and that protein and creatine supplementation may help preserve lean mass and build muscle strength during weight loss. —Lauren Manaker, SELF, 10 Mar. 2026

Shapiro says that there is no advantage to putting something like creatine or protein in water versus a shake from a nutritional standpoint. —Audrey Noble, Vogue, 9 Mar. 2026

Some studies on high-dose creatine (20 g/day) have found improvements in certain cognitive domains. —Sarah Bence, Verywell Health, 3 Mar. 2026

The mutation results in a block in the transport of creatine to the brain and muscle. —Leanne Miller, CNBC, 2 Mar. 2026

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine