creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

How Creatine Affects Muscle Mass and Fat Loss Taking creatine does not directly lead to weight loss. —Sarah Anzlovar, Verywell Health, 10 Feb. 2026

Creatine supplements that work and don’t taste chalky This Jolly Rancher Cherry creatine delivers 5 grams per serving (the standard effective dose backed by research). —Bestreviews, Mercury News, 10 Feb. 2026

Foods rich in protein, creatine, omega-3s, and antioxidants may help reduce muscle soreness, improve recovery, and enhance performance. —Merve Ceylan, Health, 3 Feb. 2026

The beta-alanine also provides a mild boost, and creatine supports strength gains over time. —Bestreviews, Chicago Tribune, 3 Feb. 2026

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine