: a white crystalline nitrogenous substance C4H9N3O2 found especially in the muscles of vertebrates either free or as phosphocreatine
also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web
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Second, fueling the cellular engine with proper nutrition, like complex carbs, and considering supplements like creatine, alongside hormonal rhythms. Luciana Paulise, Forbes.com, 23 July 2026 Research suggests creatine may help support healthy aging by preserving muscle function when paired with regular exercise. Sara Hoffman, Verywell Health, 20 July 2026 Halle Berry has publicly discussed taking magnesium and creatine to manage brain fog, giving supplement stacking mainstream visibility. Hanna Wickes, Fort Worth Star-Telegram, 16 July 2026 Halle Berry has publicly discussed taking magnesium and creatine for brain fog. Hanna Wickes, Miami Herald, 16 July 2026 See All Example Sentences for creatine

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Time Traveler
The first known use of creatine was in 1840

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Cite this Entry

“Creatine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/creatine. Accessed 28 Jul. 2026.

Medical Definition

: a white crystalline nitrogenous substance C4H9N3O2 found especially in vertebrate muscle either free or as phosphocreatine

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