creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Most recently, the brand introduced muscle-boosting creatine gummies in January. —Noor Lobad, Footwear News, 27 Jan. 2026

Despite decades of research supporting creatine’s benefits, the category has remained largely stagnant, defined by powders, poor absorption, and a narrow focus on bodybuilding. —Gabby Shacknai, Forbes.com, 26 Jan. 2026

The Cost The cost of creatine may differ by form. —Kirstyn Hill, Health, 21 Jan. 2026

Other ingredients, such as creatine and beta-alanine, may remain in the body longer but do not cause stimulation and are unlikely to be felt after a workout ends. —Morgan Pearson, Verywell Health, 21 Jan. 2026

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine