creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

In one small study, individuals with depression saw improvement with 3 to 5 grams of daily creatine, but individuals with bipolar disorder saw symptoms worsen. —Angelica Stabile, FOXNews.com, 11 Oct. 2025

The Gay Grim Reaper knocks at your 28-year-old door with a scythe in one hand and a tub of creatine in the other. —Samantha Allen, Them., 10 Oct. 2025

Tips to Maximize Your Results To maximize your results, pair your creatine consumption with a resistance training regimen that has enough intensity and frequency to promote future strength gains. —Sherri Gordon, Health, 1 Oct. 2025

While your body naturally produces some creatine, can maximizing on it really deliver the benefits influencers are claiming? —Brittney Melton, NPR, 5 Sep. 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine