creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Key Takeaways There is limited research on how long creatine stays in your system, but generally speaking, creatine stores decrease slowly. —Emily Brown, Verywell Health, 11 Dec. 2025

Overall, Norwitz found that, in his personal experience, the sardine diet delivered high-quality protein, omega-3s and nutrients such as creatine and CoQ10 that boosted energy, burned fat and still preserved muscle. —Deirdre Bardolf, FOXNews.com, 2 Dec. 2025

Based on current research, both types of creatine are safe to consume daily and are good for building muscle and lowering body fat. —Health, 28 Nov. 2025

However, lifestyle, age, and diet can all determine your natural stores of creatine. —Brianna Peters, Vogue, 9 Nov. 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine