creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Peterson has since said an increase in his creatine intake was to blame for his cramping problems. —Rohan Nadkarni, NBC news, 24 June 2026

Researchers followed rugby players through three weeks of creatine supplementation, tracking testosterone, dihydrotestosterone (DHT) and the ratio between the two. —Samantha Agate, Miami Herald, 22 June 2026

The connection traces back to a 2009 study in the Clinical Journal of Sport Medicine that followed rugby players taking creatine for three weeks. —Samantha Agate, Fort Worth Star-Telegram, 22 June 2026

What the Research Shows A 2025 study followed 15 women with a mean age of 54, including five in perimenopause and 10 in postmenopause, over 14 weeks of twice-weekly total body strength training paired with creatine supplementation. —Samantha Agate, Kansas City Star, 17 June 2026

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine