creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Key Takeaways Most people can get creatine from their diet by eating red meat, lean meats, and seafood. —Lana Barhum, Verywell Health, 28 Aug. 2025

If your creatinine level comes back unusually high from creatine supplementation, the laboratory might investigate further or require you to retest. —Jillian Kubala, Health, 26 Aug. 2025

Naturally found in muscle and brain tissue, creatine helps women maintain strength, muscle mass, and cognitive clarity as hormone levels shift. —Kate Donnelly, Forbes.com, 28 July 2025

As a result, creatine supplements have become a popular way to increase the creatine in the muscles. —Joshua Rapp Learn, Discover Magazine, 11 July 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine