creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

For the best results, choose creatine monohydrate, take 3–5 mg daily, and stay consistent with your workouts. —Jenna Anderson, Health, 17 Oct. 2025

Including both creatine and protein in your diet may give you even better results for your overall workout performance and recovery. —Jessica Swirble, Verywell Health, 14 Oct. 2025

In one small study, individuals with depression saw improvement with 3 to 5 grams of daily creatine, but individuals with bipolar disorder saw symptoms worsen. —Angelica Stabile, FOXNews.com, 11 Oct. 2025

The Gay Grim Reaper knocks at your 28-year-old door with a scythe in one hand and a tub of creatine in the other. —Samantha Allen, Them., 10 Oct. 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine