1
: of, relating to, or consisting of cortex
2
: involving or resulting from the action or condition of the cerebral cortex

Examples of cortical in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The brain’s surface has ridges and valleys, and CTE tangles are found in the depths of those valleys, called the cortical sulci, and surround blood vessels. — Alexandra Pattillo, Scientific American, 23 Sep. 2026 In a recent Nature study, Terral and Renata Batista-Brito, who runs the lab, report a population of cortical cells that challenges that assumption. — Jacek Krywko, ArsTechnica, 18 Sep. 2026 While experts recognize the immense scientific potential of the findings, some warn that the ability to create hybrid mouse-human cortical brain cells could bring us closer than ever to a concerning ethical boundary. — Mike McRae 17, New Atlas, 17 Sep. 2026 Human brain analyses validate findings To determine whether their findings translate to humans, the researchers obtained cortical samples from four human individuals aged 67 to 96. — Kristel Tjandra, Hartford Courant, 5 June 2026 See All Example Sentences for cortical

Word History

First Known Use

1671, in the meaning defined at sense 1

Time Traveler
The first known use of cortical was in 1671

Cite this Entry

“Cortical.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cortical. Accessed 29 Sep. 2026.

Medical Definition

cortical

adjective
1
: of, relating to, or consisting of cortex
cortical tissue
2
: involving or resulting from the action or condition of the cerebral cortex
cortical blindness
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