Definition of come down from
1 : to move or fall downward from (somewhere or something) I'd like you to come down from that ledge before you fall down.
2 : to be passed on from (a former time) This is a story that has come down from ancient times.
3 informal : to stop feeling the effect of (an illegal drug) : to stop being high on (a drug) an addict who is coming down from heroin
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