Definition of clinical depression
: a serious mood disorder involving one or more episodes of intense psychological depression or loss of interest or pleasure that lasts two or more weeks and is accompanied by irritability, fatigue, poor concentration, sleep disturbances, weight gain or loss, feelings of worthlessness or guilt, and sometimes suicidal tendencies : major depression, major depressive disorder Mild depression is a normal condition, a sadness brought on by life's circumstances. Clinical depression, on the other hand, is a sadness so deep that it can lead to suicide if left untreated.— Brenda Lane Richardson
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