clinical depression

noun

: a serious mood disorder involving one or more episodes of intense psychological depression or loss of interest or pleasure that lasts two or more weeks and is accompanied by irritability, fatigue, poor concentration, sleep disturbances, weight gain or loss, feelings of worthlessness or guilt, and sometimes suicidal tendencies : major depression, major depressive disorder
Mild depression is a normal condition, a sadness brought on by life's circumstances. Clinical depression, on the other hand, is a sadness so deep that it can lead to suicide if left untreated.Brenda Lane Richardson

Examples of clinical depression in a Sentence

Recent Examples on the Web His self-loathing became full-on clinical depression. Jesse David Fox, Vulture, 16 Mar. 2024 Murder-suicides can stem from many reasons, including extreme stress, clinical depression, loss and more. Shelby Slade, The Arizona Republic, 15 Jan. 2024 Also important to note: Sometimes what feels or looks like caregiver burnout could be a more serious concern like depression or anxiety; other times, burnout that's not relieved can become clinical depression or an anxiety disorder. Cassie Shortsleeve, Parents, 21 May 2024 Depression itself is sort of an umbrella term or category that contains a range of emotional conditions such as burnout, mild depression, and major/clinical depression, as well as seasonal affective disorder (SAD), postpartum depression, etc. Dominique Fluker, Essence, 8 May 2024 Indeed, Cobain had long suffered from clinical depression, having been diagnosed with it in high school. Gillian Telling, Peoplemag, 2 Apr. 2024 Depressive feelings as a result of loss are appropriate emotions, but clinical depression is a severe form of depression that’s the result of a mood disorder that causes persistent feelings of depression along with a lack of interest in living your life. Sara Novak, Discover Magazine, 13 Dec. 2023 Despite her success, Hidalgo has been battling clinical depression and experienced suicidal thoughts that led her to check herself into an inpatient treatment center in Ohio in July. Ed O'Keefe, CBS News, 6 Oct. 2023 The law does not differentiate between mental illnesses that can be ameliorated with medication, such as schizophrenia, bipolar and clinical depression, and those that are incurable, such as dementia. Jessica Wapner, Scientific American, 15 Aug. 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'clinical depression.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1937, in the meaning defined above

Time Traveler
The first known use of clinical depression was in 1937

Dictionary Entries Near clinical depression

Cite this Entry

“Clinical depression.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/clinical%20depression. Accessed 18 Jul. 2024.

Medical Definition

clinical depression

noun
: a serious mood disorder involving one or more episodes of intense psychological depression or loss of interest or pleasure that lasts two or more weeks and is accompanied by irritability, fatigue, poor concentration, sleep disturbances, weight gain or loss, feelings of worthlessness or guilt, and sometimes suicidal tendencies : major depression, major depressive disorder
Cases of clinical depression present doctors with a nasty diagnostic challenge: The malady, which strikes about 10% of the population, comes in myriad forms, each requiring different treatments.Science
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