bloodstream

noun

blood·​stream ˈbləd-ˌstrēm 

1

: the flowing blood in a circulatory system

2

: a mainstream of power or vitality

… introduce into the economic bloodstream a large amount of money …

—Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.

Recent Examples on the Web

Where most garage rock is designed to punch you in the gut, Twisted Teens’ songs seep into your bloodstream, tugging at the heartstrings while occasionally inducing hallucinations. — Stuart Berman, Pitchfork, 5 Nov. 2026

Whole-body therapies, which come in pills, patches, sprays, gels and a vaginal ring, deliver doses of hormones into the bloodstream at levels high enough to have significant effects on symptoms like hot flashes. — Laura Ungar, Los Angeles Times, 3 Nov. 2026

For the next four years, roughly once a month, a Lyft driver took Kewman to Stanford, where a nurse infused either lecanemab or saline into his bloodstream. — Manvir Singh, New Yorker, 2 Nov. 2026

As a result, your digestive system removes cholesterol from the bloodstream. — Abby Norman, Verywell Health, 2 Nov. 2026

Word History

First Known Use

13th century, in the meaning defined at sense 1

Rhymes for bloodstream

• abeam
• airstream
• daydream
• downstream
• esteem
• extreme
• grapheme
• hakim
• hornbeam
• lexeme
• mainstream
• midstream

Kids Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a circulatory system