bloodstream

noun

blood·​stream ˈbləd-ˌstrēm 

1

: the flowing blood in a circulatory system

2

: a mainstream of power or vitality

… introduce into the economic bloodstream a large amount of money …

—Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.

Recent Examples on the Web

Vaniček was responsible for that arachnophobia-nightmare fodder Infested from 2023, and the idea of injecting some late New French Extremity into the Evil Dead bloodstream is tantalizing. — David Fear, Rolling Stone, 10 July 2026

At this point in life, estradiol levels are consistently below 20 pg/mL and estrone becomes the more relevant form of estrogen in the bloodstream. — Jamie Ducharme, Health, 10 July 2026

Oxytocin is a hormone produced in the part of the brain called the hypothalamus and is released from the pituitary gland into the bloodstream. — Camille Hoffman, The Conversation, 7 July 2026

The coroner said that the patient died of a fat embolism, when fat globules entered the bloodstream due to abdominal surgical procedure and liposuction, KGET reported. — David Chiu, PEOPLE, 6 July 2026

Word History

First Known Use

13th century, in the meaning defined at sense 1

Rhymes for bloodstream

• abeam
• airstream
• daydream
• downstream
• esteem
• extreme
• grapheme
• hakim
• hornbeam
• lexeme
• mainstream
• midstream

Kids Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a circulatory system