bloodstream

noun

blood·​stream ˈbləd-ˌstrēm 

1

: the flowing blood in a circulatory system

2

: a mainstream of power or vitality

… introduce into the economic bloodstream a large amount of money …

—Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.

Recent Examples on the Web

Hostile powers, particularly Russia, are using this free-for-all to inject lies, designed to inflame antagonisms or simply muddy the waters, into the bloodstream of democracy. —Adrian Wooldridge, Twin Cities, 6 Dec. 2025

Trophoblasts, the placental cells that invade maternal tissue and connect with the mother’s bloodstream, rely on precise cellular choreography during early pregnancy. —Daniella Gray, MSNBC Newsweek, 5 Dec. 2025

Kurt's key takeaways The idea of a grain-sized robot navigating the bloodstream sounds bold, yet the science behind it is moving forward fast. —Kurt Knutsson, FOXNews.com, 4 Dec. 2025

Soluble fiber slows digestion, which helps gradually release glucose into the bloodstream. —Mira Miller, Verywell Health, 4 Dec. 2025

Word History

First Known Use

13th century, in the meaning defined at sense 1

Rhymes for bloodstream

• abeam
• airstream
• daydream
• downstream
• esteem
• extreme
• grapheme
• hakim
• hornbeam
• lexeme
• mainstream
• midstream

Kids Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a circulatory system