bloodstream

noun

blood·​stream ˈbləd-ˌstrēm How to pronounce bloodstream (audio)
1
: the flowing blood in a circulatory system
2
: a mainstream of power or vitality
… introduce into the economic bloodstream a large amount of money …Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Who These Jobs Really Are The reforms are aimed at the policy bloodstream of the administrative state. James Broughel, Forbes.com, 30 Jan. 2026 The delivery method has the advantage of allowing direct absorption into the bloodstream without requiring an injection. Ana Castelain, Bloomberg, 28 Jan. 2026 Maybe by whatever was floating through his bloodstream—Adi didn’t know. Jonathan Miles, Harpers Magazine, 27 Jan. 2026 In more severe cases, the infection can spread to the bloodstream and lead to more serious complications. Moná Thomas, PEOPLE, 27 Jan. 2026 See All Example Sentences for bloodstream

Word History

First Known Use

13th century, in the meaning defined at sense 1

Time Traveler
The first known use of bloodstream was in the 13th century

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Cite this Entry

“Bloodstream.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/bloodstream. Accessed 5 Feb. 2026.

Kids Definition

bloodstream

noun
blood·​stream -ˌstrēm How to pronounce bloodstream (audio)
: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun
blood·​stream -ˌstrēm How to pronounce bloodstream (audio)
: the flowing blood in a circulatory system

More from Merriam-Webster on bloodstream

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