bloodstream

noun

blood·​stream ˈbləd-ˌstrēm 

1

: the flowing blood in a circulatory system

2

: a mainstream of power or vitality

… introduce into the economic bloodstream a large amount of money …

—Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.

Recent Examples on the Web

In 2025, her sister Erin launched a GoFundMe to help with medical expenses after Eggers was hospitalized with severe pneumonia and a bacterial infection in her bloodstream. — Deirdre Durkan, PEOPLE, 4 Sep. 2026

Estradiol transdermal patches, which deliver the estrogen hormone directly into the bloodstream, are used to ease menopause symptoms such as mood swings, hot flashes and sleep disturbances. — Sriparna Roy, USA Today, 3 Sep. 2026

As glucose enters your bloodstream, your blood sugar naturally rises. — Brandi Jones, Verywell Health, 2 Sep. 2026

For the first time, Gallup asked about consumption of nicotine pouches, small sachets placed between the upper lip and gum that allow direct absorption of nicotine into the bloodstream. — Dario Sabaghi, Forbes.com, 29 Aug. 2026

Word History

First Known Use

13th century, in the meaning defined at sense 1

Rhymes for bloodstream

• abeam
• airstream
• daydream
• downstream
• esteem
• extreme
• grapheme
• hakim
• hornbeam
• lexeme
• mainstream
• midstream

Kids Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a circulatory system