bloodstream

noun

blood·​stream ˈbləd-ˌstrēm 

1

: the flowing blood in a circulatory system

2

: a mainstream of power or vitality

… introduce into the economic bloodstream a large amount of money …

—Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.

Recent Examples on the Web

This allows the liver to remove more LDL cholesterol from the bloodstream. — Fran Kritz, Verywell Health, 24 July 2026

It’s also known for having a variant that can go metastatic, traveling via the bloodstream to invade other organs, particularly the liver, but also the lungs, eyes, and brain. — Beth Mole, ArsTechnica, 23 July 2026

These changes allow glucose to enter the bloodstream more quickly. — Brianna Tobritzhofer, Health, 23 July 2026

Fiber helps manage your blood sugar levels by slowing the absorption of sugar into your bloodstream. — Lauren Jarvis-Gibson july 21, Charlotte Observer, 21 July 2026

Word History

First Known Use

13th century, in the meaning defined at sense 1

Rhymes for bloodstream

• abeam
• airstream
• daydream
• downstream
• esteem
• extreme
• grapheme
• hakim
• hornbeam
• lexeme
• mainstream
• midstream

Kids Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a circulatory system