1
: the flowing blood in a circulatory system
2
: a mainstream of power or vitality
… introduce into the economic bloodstream a large amount of money …Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
But the lawsuit states that Griego suffered an amniotic fluid embolism (AFE) during the delivery, meaning the fluid surrounding the fetus or fetal cells had entered her bloodstream, which can cause sudden heart-lung collapse and massive bleeding. Alyssa Goldberg, USA Today, 24 Aug. 2026 Now, new research reveals this kind of high-intensity training provokes a remarkably robust response throughout the bloodstream. Will Stone, NPR, 24 Aug. 2026 The fungus can cause everything from skin infections to life-threatening bloodstream infections. Don Sweeney, Sacbee.com, 21 Aug. 2026 The Centers for Disease Control and Prevention explains that having too much blood sugar in the bloodstream will overwhelm our liver and muscles that normally store blood sugar and cause the insulin in our bodies to store any excess in other places. Audrey Noble, Vogue, 20 Aug. 2026 See All Example Sentences for bloodstream

Word History

First Known Use

13th century, in the meaning defined at sense 1

Time Traveler
The first known use of bloodstream was in the 13th century

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Cite this Entry

“Bloodstream.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/bloodstream. Accessed 26 Aug. 2026.

Kids Definition

bloodstream

noun
: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun
: the flowing blood in a circulatory system
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