bivalent

adjective
bi·​va·​lent | \ (ˌ)bī-ˈvā-lənt How to pronounce bivalent (audio) , ˈbī-və- How to pronounce bivalent (audio) \

Definition of bivalent

 (Entry 1 of 2)

1 chemistry : having a valence of two : divalent bivalent calcium
2 genetics : associated in pairs in synapsis bivalent chromosomes
3 immunology : having two combining sites a bivalent antibody capable of binding to two molecules of an antigen
4 medical : conferring immunity to two diseases or two serotypes a bivalent vaccine

bivalent

noun

Definition of bivalent (Entry 2 of 2)

: a pair of synaptic chromosomes

Examples of bivalent in a Sentence

Recent Examples on the Web: Noun Once those bivalent vaccine boosters are authorized by the FDA and the CDC, the first deliveries by both manufacturers will be received in the early fall, Health and Human Services said in a news release. Kristen Welker, NBC News, 29 July 2022 Moderna's bivalent booster vaccine candidate contains components of both Moderna's original Covid-19 vaccine and a vaccine that targets the Omicron variant. Jen Christensen, CNN, 28 June 2022 Sure, a bivalent vaccine booster might spur the immune system to generate more antibodies than a regular booster, but that doesn’t necessarily mean recipients would be better off, Offit said in an interview. Melissa Healy, Los Angeles Times, 12 July 2022 To get the total cost of vaccines, analysts combined the individual costs of the Bordetella, DAPP, bivalent influenza, leptospirosis, Lyme disease and rabies shots. Claire Rafford, The Indianapolis Star, 7 July 2022 Experts advising them, including Centers for Disease Control and Prevention officials, agreed with that urgency at the Tuesday meeting, with many recommending the bivalent option aimed partly at Omicron subvariants. Noah Weiland, New York Times, 30 June 2022 The vast majority of data available on next-generation boosters involves BA.1, either in bivalent formulas or alone. Beth Mole, Ars Technica, 30 June 2022 The bivalent candidates increased titers by 9.1-fold for the lower dose and 10.9-fold for the higher one. Matthew Herper, STAT, 28 June 2022 Pfizer and its German partner BioNTech, however, found that a vaccine that targets a single variant of the virus, BA. 1, was better than a bivalent formulation. Katie Shepherd, BostonGlobe.com, 28 June 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'bivalent.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of bivalent

Adjective

1869, in the meaning defined at sense 1

Noun

circa 1934, in the meaning defined above

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Time Traveler for bivalent

Time Traveler

The first known use of bivalent was in 1869

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Dictionary Entries Near bivalent

-bius

bivalent

bivalve

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Cite this Entry

“Bivalent.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/bivalent. Accessed 8 Aug. 2022.

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More Definitions for bivalent

bivalent

adjective
bi·​va·​lent | \ (ˈ)bī-ˈvā-lənt How to pronounce bivalent (audio) \

Medical Definition of bivalent

 (Entry 1 of 2)

1a : divalent bivalent calcium
b : having two combining sites a bivalent antibody capable of binding to two molecules of an antigen
2 : associated in pairs in synapsis bivalent chromosomes
3 : conferring immunity to two diseases or two serotypes a bivalent vaccine protecting against hepatitis A and hepatitis B

bivalent

noun

Medical Definition of bivalent (Entry 2 of 2)

: a pair of synaptic chromosomes

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