base-pair

verb
\ ˈbās-ˌper How to pronounce base-pair (audio) \
base-paired; base-pairing; base-pairs

Definition of base-pair

 (Entry 1 of 2)

intransitive verb

: to participate in formation of a base pair adenine base-pairs with thymine

base pair

noun

Definition of base pair (Entry 2 of 2)

: one of the pairs of nucleotide bases on complementary strands of nucleic acid that consist of a purine on one strand joined to a pyrimidine on the other strand by hydrogen bonds holding together the two strands much like the rungs of a ladder and that include adenine linked to thymine in DNA or to uracil in RNA and guanine linked to cytosine in both DNA and RNA

Examples of base-pair in a Sentence

Recent Examples on the Web: Noun These include base editing—which unzips the DNA enough to swap a single base pair for another—and prime editing, which does that, and more, with just a little nick on one side of the DNA double helix. Megan Molteni, Wired, "In Embryos, Crispr Can Cut Out Whole Chromosomes—That's Bad," 29 Oct. 2020 Procedure Pick a prepared strip of paper (a base pair) and stick one end to one backbone and the other end to the other parallel backbone. Scientific American, "Colorful Double Helix," 9 Aug. 2018 That’s significant, Chiu said, because the average difference between most strains of coronavirus found today and the original strain is 10 to 12 base pairs. Peter Fimrite, SFChronicle.com, "On the trail of the coronavirus: How scientists track the pathogen," 18 May 2020 Those mutations occurred among the nearly 30,000 base pairs of RNA that other scientists say make up the coronavirus’s genome. Los Angeles Times, "Scientists say a now-dominant strain of the coronavirus appears to be more contagious than original," 5 May 2020 The mutations occurred among the nearly 30,000 base pairs of RNA that other scientists say make up the coronavirus's genome. Mica Soellner, Washington Examiner, "Scientists find more contagious, mutant coronavirus in new study," 5 May 2020 The new coronavirus is a little larger than typical viruses, with about 30,000 base pairs. Amanda Morris, azcentral, "Coronavirus in Arizona: Genetic mapping now searching for sources of infections in the state," 6 Mar. 2020 Changing the Rules The ability to increase the number of base pairs or amino acids changes the rules of that game entirely. Quanta Magazine, "Is a Bigger Genetic Code Better? Get Ready to Find Out," 2 Jan. 2018 Adding those base pairs back in the lab made the virus much better at replicating in several cell culture models. Kai Kupferschmidt, Science | AAAS, "Mutations can reveal how the coronavirus moves—but they’re easy to overinterpret," 9 Mar. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'base-pair.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of base-pair

Verb

1973, in the meaning defined above

Noun

1955, in the meaning defined above

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Time Traveler for base-pair

Time Traveler

The first known use of base-pair was in 1955

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Cite this Entry

“Base-pair.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/base-pair. Accessed 19 Jan. 2021.

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More Definitions for base-pair

base pair

noun
\ -ˈpa(ə)r, -ˈpe(ə)r How to pronounce base pair (audio) \

Medical Definition of base pair

 (Entry 1 of 2)

: one of the pairs of nucleotide bases on complementary strands of nucleic acid that consist of a purine on one strand joined to a pyrimidine on the other strand by hydrogen bonds holding together the two strands much like the rungs of a ladder and that include adenine linked to thymine in DNA or to uracil in RNA and guanine linked to cytosine in both DNA and RNA

Medical Definition of base pair (Entry 2 of 2)

: to participate in formation of a base pair adenine base pairs with thymine

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