base-pair

verb
\ ˈbās-ˌper How to pronounce base-pair (audio) \
base-paired; base-pairing; base-pairs

Definition of base-pair

 (Entry 1 of 2)

intransitive verb

: to participate in formation of a base pair adenine base-pairs with thymine

base pair

noun

Definition of base pair (Entry 2 of 2)

: one of the pairs of nucleotide bases on complementary strands of nucleic acid that consist of a purine on one strand joined to a pyrimidine on the other strand by hydrogen bonds holding together the two strands much like the rungs of a ladder and that include adenine linked to thymine in DNA or to uracil in RNA and guanine linked to cytosine in both DNA and RNA

Examples of base-pair in a Sentence

Recent Examples on the Web: Noun Today Twist charges nine cents a base pair for DNA, a nearly tenfold decrease from the industry standard a decade ago. New York Times, 24 Nov. 2021 The PacBio tech uses lasers to examine 20,000 base pair sequences of DNA at a time repeatedly to create a highly accurate readout, reports STAT. Elizabeth Gamillo, Smithsonian Magazine, 18 June 2021 So far treating sickle cell via base pair editing has only been shown to work in mice, not humans. Leah Rosenbaum, Forbes, 2 June 2021 By contrast, the thyroid cancers in the Cancer Genome Atlas and in the control group of 81 unexposed people from the area were more likely to be caused by single-point mutations, where just one single base pair of the DNA is changed. Sara Harrison, Wired, 26 Apr. 2021 Snowshoes are meant to be worn with a base pair of boots. Lauren Levy, NBC News, 24 Feb. 2021 These include base editing—which unzips the DNA enough to swap a single base pair for another—and prime editing, which does that, and more, with just a little nick on one side of the DNA double helix. Megan Molteni, Wired, 29 Oct. 2020 Procedure Pick a prepared strip of paper (a base pair) and stick one end to one backbone and the other end to the other parallel backbone. Scientific American, 9 Aug. 2018 That’s significant, Chiu said, because the average difference between most strains of coronavirus found today and the original strain is 10 to 12 base pairs. Peter Fimrite, SFChronicle.com, 18 May 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'base-pair.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of base-pair

Verb

1973, in the meaning defined above

Noun

1955, in the meaning defined above

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Time Traveler for base-pair

Time Traveler

The first known use of base-pair was in 1955

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Dictionary Entries Near base-pair

base on balls

base-pair

base pair

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Cite this Entry

“Base-pair.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/base-pair. Accessed 18 Jan. 2022.

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More Definitions for base-pair

base pair

noun
\ -ˈpa(ə)r, -ˈpe(ə)r How to pronounce base pair (audio) \

Medical Definition of base pair

 (Entry 1 of 2)

: one of the pairs of nucleotide bases on complementary strands of nucleic acid that consist of a purine on one strand joined to a pyrimidine on the other strand by hydrogen bonds holding together the two strands much like the rungs of a ladder and that include adenine linked to thymine in DNA or to uracil in RNA and guanine linked to cytosine in both DNA and RNA

base pair

intransitive verb

Medical Definition of base pair (Entry 2 of 2)

: to participate in formation of a base pair adenine base pairs with thymine

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