aplastic anemia


aplas·​tic anemia (ˌ)ā-ˈpla-stik- How to pronounce aplastic anemia (audio)
: anemia that is characterized by defective function of the blood-forming organs (such as the bone marrow) and is caused by toxic agents (such as chemicals or X-rays) or is idiopathic in origin

Examples of aplastic anemia in a Sentence

Recent Examples on the Web The bone marrow and gastrointestinal tract are especially sensitive, and people may develop aplastic anemia, a rare blood disorder in which the marrow cannot make new blood cells, and a devastating and rapid form of leukemia. Monique Brouillette, Popular Mechanics, 28 Aug. 2023 Cameron, then 6, had an immune system compromised first by severe aplastic anemia and then by the marrow transplant. Dave Kallmann, Journal Sentinel, 23 Apr. 2023 Non-Hodgkin’s lymphoma, lung cancer, prostate cancer, aplastic anemia, colon cancer, liver cancer, esophageal cancer, asbestosis, Ewing’s sarcoma, emphysema, cancer of the brain, cancer of the heart: these are some of the illnesses that appeared in our town. Rosemary McClure, Los Angeles Times, 26 Mar. 2021 Along with hypothyroid conditions, perchlorate has also been implicated in aplastic anemia and agranulocytosis, conditions characterized by a life-threatening deficiency of blood cells. David Warmflash, Discover Magazine, 20 June 2016 Specialists conducted two bone marrow biopsies for potential blood cancer and aplastic anemia, in which the bone marrow fails to produce red blood cells, white blood cells and platelets. Amitha Kalaichandran, Discover Magazine, 9 Aug. 2020 And then the new thing, aplastic anemia, was completely unrelated. Dave Kallmann, Journal Sentinel, 25 Dec. 2022 For example, Marie Curie died of aplastic anemia, resulting from years of radiation exposure. Allison Futterman, Discover Magazine, 10 Feb. 2022 In March 2020, my wife was diagnosed with severe aplastic anemia and received a lifesaving — though terrifying — bone marrow transplant in April 2020. Lisa M. Bolton, Washington Post, 17 June 2022 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'aplastic anemia.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1928, in the meaning defined above

Time Traveler
The first known use of aplastic anemia was in 1928

Dictionary Entries Near aplastic anemia

Cite this Entry

“Aplastic anemia.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/aplastic%20anemia. Accessed 28 Feb. 2024.

Medical Definition

aplastic anemia

: severe anemia that results from defective functioning of the bone marrow with an abnormal reduction in blood cells and that is characterized especially by headache, fatigue, paleness, fever, recurrent infections, bruising or rashes, and rapid or irregular heartbeat

Note: Aplastic anemia is often of unknown cause but may occur as a congenital or inherited condition (as in Fanconi's anemia) or be caused by exposure to toxic agents (such as chemicals, drugs, or X-rays) or infection with pathogens (such as hepatitis virus or HIV).

called also hypoplastic anemia

More from Merriam-Webster on aplastic anemia

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!