antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
Synonyms of antagonizenext

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Produced through his Loser Films shingle, the film is about a group of small-town amateur stuntmen whose days revolve around drinking, antagonizing their community, and filming crude, Jackass-style stunts. Matt Grobar, Deadline, 9 Mar. 2026 Dillon Brooks antagonizing, Devin Booker feigning indifference. Jason Quick, New York Times, 2 Mar. 2026 In 2023, the aforementioned Watts slammed Cutrone in an EW interview, over allegedly antagonizing her during an earlier challenge, which led to the pair's infamous on-air clash that resulted in Watts walking out of the judging deliberation and quitting the competition on the spot. Joey Nolfi, Entertainment Weekly, 26 Feb. 2026 Investigations have linked them to vigilante groups known as militias, which often antagonized Franco. Arkansas Online, 26 Feb. 2026 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

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Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 12 Mar. 2026.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

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