antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
Synonyms of antagonize

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Beijing has sought to navigate this ambivalence by engaging individual European governments while sidelining Brussels, a tactic that reliably antagonizes EU institutions. Yu Jie, Time, 13 May 2026 Tradwifery carries an undercurrent of trolling—a middle finger raised at anyone antagonized by women boasting about catering to their husband’s every whim. Sophie Gilbert, The Atlantic, 11 May 2026 Tollinche allegedly antagonizes people on the social media platform, and neighborhood teens have recently been gathering outside his home, knocking on his door and calling him out, according to police. Aaron Katersky, ABC News, 1 May 2026 Young has continued to antagonize New York fans, including pretending to roll dice on the Knicks logo after a 2024 victory clinched a trip to Las Vegas for the NBA Cup. Peter Sblendorio, New York Daily News, 21 Apr. 2026 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

Browse Nearby Words

Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 14 May. 2026.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

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