Definition of anathema
1a
: someone or something intensely disliked or loathed
—usually used as a predicate nominative … this notion was anathema to most of his countrymen.— Stephen Jay Gould
b
: one that is cursed by ecclesiastical authority
2a
: a ban or curse solemnly pronounced by ecclesiastical authority and accompanied by excommunication
b
: the denunciation of something as accursed
c
: a vigorous denunciation : curse
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Merriam-Webster unabridged
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The first known use of anathema was in 1582
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