amphetamine

noun

am·​phet·​amine am-ˈfe-tə-ˌmēn How to pronounce amphetamine (audio)
-mən
: a racemic compound C9H13N or one of its derivatives (such as dextroamphetamine or methamphetamine) that is a stimulant of the central nervous system, is often abused illicitly, and is used clinically especially in the form of its sulfate C9H13N·H2SO4 to treat attention deficit hyperactivity disorder and narcolepsy and formerly as a short-term appetite suppressant

Examples of amphetamine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Methamphetamines and amphetamines can cause organ damage and even death, the DEA says. Mirna Alsharif, NBC news, 20 Jan. 2026 Jacqueline was also found to have amphetamines and an antihistamine in her system, the report said. Justin Muszynski, Hartford Courant, 15 Jan. 2026 Though cocaine, which was legal in the 19th century, was the vice of many in the book, many other substances make an appearance, including cannabis, amphetamines, alcohol, acid, painkillers and even yellow paint. Tiney Ricciardi, Denver Post, 12 Jan. 2026 Inside his Volkswagen, officers recovered a metal tin that contained a powder that tested positive for the presence of amphetamines. Nick Ferraro, Twin Cities, 12 Jan. 2026 See All Example Sentences for amphetamine

Word History

First Known Use

1938, in the meaning defined above

Time Traveler
The first known use of amphetamine was in 1938

Browse Nearby Words

Cite this Entry

“Amphetamine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/amphetamine. Accessed 25 Jan. 2026.

Kids Definition

amphetamine

noun
am·​phet·​amine am-ˈfet-ə-ˌmēn How to pronounce amphetamine (audio)
-mən
: a compound or one made from it used medically to increase the activity of the central nervous system but often abused for its stimulant effects

Medical Definition

amphetamine

noun
am·​phet·​amine am-ˈfet-ə-ˌmēn How to pronounce amphetamine (audio) -mən How to pronounce amphetamine (audio)
: a racemic sympathomimetic amine C9H13N or one of its derivatives (as dextroamphetamine or methamphetamine) that is a stimulant of the central nervous system, is frequently abused illicitly often leading to dependence, and is used clinically especially in the form of its sulfate C9H13N·H2SO4 to treat attention deficit hyperactivity disorder and narcolepsy and formerly as a short-term appetite suppressant see adderall

More from Merriam-Webster on amphetamine

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!