chlor·​prom·​a·​zine klȯr-ˈprä-mə-ˌzēn How to pronounce chlorpromazine (audio)
: a phenothiazine C17H19ClN2S used chiefly as a tranquilizer especially in the form of its hydrochloride to control the symptoms of psychotic disorders (such as schizophrenia)

Examples of chlorpromazine in a Sentence

Recent Examples on the Web Meanwhile, new pharmaceuticals like chlorpromazine (also known as Thorazine) burst onto the scene, holding the promise to treat people with mental afflictions without the need for around-the-clock supervision. Greg Rosalsky, NPR, 16 Apr. 2024 Drugs that may cause a problem include barbiturates, benzodiazepines, chlorpromazine, reserpine, and tricyclic antidepressants. Katie Wiseman, The Indianapolis Star, 19 Jan. 2024 Some common first-generation antipsychotics include chlorpromazine, haloperidol, perphenazine, and fluphenazine; second-generation drugs include olanzapine, risperidone, quetiapine, aripiprazole, ziprasidone, lurasidone, cariprazine, and paliperidone. Ashley Abramson, SELF, 11 Feb. 2022 Researchers eventually discovered that drugs like chlorpromazine might work by dampening the transmission of dopamine. WIRED, 10 Feb. 2023 For persistent hiccups, doctors sometimes turn to prescriptions like gabapentin, baclofen and chlorpromazine. Marisa Sloan, Discover Magazine, 25 Jan. 2023 That only began to change in the 1950s with the development of the first antipsychotic drugs, foremost of which was chlorpromazine, also known as Thorazine. Christian Millman, Discover Magazine, 23 Oct. 2019 The drug is chlorpromazine, which has also been used to treat psychotic disorders. Anna Kaufman, USA TODAY, 23 July 2022 Or the life-saving psychiatric medication chlorpromazine, now known as Thorazine, created in 1951. Robert Pearl, Forbes, 13 June 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'chlorpromazine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


chlor- + propyl + methyl + azine

First Known Use

1952, in the meaning defined above

Time Traveler
The first known use of chlorpromazine was in 1952

Dictionary Entries Near chlorpromazine

Cite this Entry

“Chlorpromazine.” Dictionary, Merriam-Webster, Accessed 21 May. 2024.

Medical Definition


chlor·​prom·​a·​zine klōr-ˈpräm-ə-ˌzēn, klȯr- How to pronounce chlorpromazine (audio)
: a phenothiazine derivative that has antipsychotic, sedative, and antiemetic properties and is used in the form of its hydrochloride C17H19ClN2S·HCl especially to manage the symptoms of psychotic disorders (as schizophrenia) see largactil, thorazine

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