agran·​u·​lo·​cy·​to·​sis | \ ˌā-ˌgran-yə-lō-ˌsī-ˈtō-səs How to pronounce agranulocytosis (audio) \
plural agranulocytoses\ ˌā-​ˌgran-​yə-​lō-​ˌsī-​ˈtō-​ˌsēz How to pronounce agranulocytoses (audio) \

Definition of agranulocytosis

: an acute febrile condition marked by severe decrease in blood granulocytes and often associated with the use of certain drugs

Examples of agranulocytosis in a Sentence

Recent Examples on the Web The drug may cause agranulocytosis, a dangerous lowering of white blood cells that puts patients at risk of serious infections, according to Berman., "Pulling Iron From Brain May Offer Hope in Alzheimer’s Fight," 29 Nov. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'agranulocytosis.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of agranulocytosis

1922, in the meaning defined above

History and Etymology for agranulocytosis

borrowed from German Agranulozytose, from a- a- entry 2 + Granulozyt granulocyte + -ose -osis

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The first known use of agranulocytosis was in 1922

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Cite this Entry

“Agranulocytosis.” Dictionary, Merriam-Webster, Accessed 13 Aug. 2020.

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agran·​u·​lo·​cy·​to·​sis | \ ˌā-ˌgran-yə-lō-ˌsī-ˈtō-səs How to pronounce agranulocytosis (audio) \
plural agranulocytoses\ -​ˌsēz How to pronounce agranulocytoses (audio) \

Medical Definition of agranulocytosis

: an acute blood disorder that is marked by a decrease of circulating granulocytes (such as neutrophils) and is characterized especially by weakness, chills, swollen neck, sore throat, mouth ulcers, and jaundice

Note: Agranulocytosis results from a decline in the production of granulocytes or from granulocyte destruction. It is typically an acquired condition occurring as a side effect of certain drugs or chemotherapy or sometimes as a complication of various medical conditions (such as infection, autoimmune disease, or aplastic anemia).

called also agranulocytic angina, granulocytopenia

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