agranulocytosis

noun

agran·​u·​lo·​cy·​to·​sis ˌā-ˌgran-yə-lō-ˌsī-ˈtō-səs 

plural agranulocytoses ˌā-ˌgran-yə-lō-ˌsī-ˈtō-ˌsēz 

: an acute febrile condition marked by severe decrease in blood granulocytes and often associated with the use of certain drugs

Examples of agranulocytosis in a Sentence

Recent Examples on the Web

To prevent and rapidly address cases of agranulocytosis, the FDA requires clozapine’s manufacturers to jointly administer the clozapine REMS program. — Brian Barnett, STAT, 9 May 2022

The drug may cause agranulocytosis, a dangerous lowering of white blood cells that puts patients at risk of serious infections, according to Berman. — Bloomberg.com, 29 Nov. 2017

Along with hypothyroid conditions, perchlorate has also been implicated in aplastic anemia and agranulocytosis, conditions characterized by a life-threatening deficiency of blood cells. — David Warmflash, Discover Magazine, 20 June 2016

Word History

Etymology

borrowed from German Agranulozytose, from a- a- entry 2 + Granulozyt granulocyte + -ose -osis

First Known Use

1922, in the meaning defined above

Rhymes for agranulocytosis

• antituberculosis
• arteriosclerosis
• neurofibromatosis
• acanthosis
• acidosis
• alkalosis
• amaurosis
• ankylosis
• asbestosis
• brucellosis
• cyanosis
• dermatosis

Medical Definition

agranulocytosis

noun

agran·​u·​lo·​cy·​to·​sis ˌā-ˌgran-yə-lō-ˌsī-ˈtō-səs 

plural agranulocytoses -ˌsēz 

: an acute blood disorder that is marked by a decrease of circulating granulocytes (such as neutrophils) and is characterized especially by weakness, chills, swollen neck, sore throat, mouth ulcers, and jaundice

Note: Agranulocytosis results from a decline in the production of granulocytes or from granulocyte destruction. It is typically an acquired condition occurring as a side effect of certain drugs or chemotherapy or sometimes as a complication of various medical conditions (such as infection, autoimmune disease, or aplastic anemia).

called also agranulocytic angina, granulocytopenia