1
: not opposed
an unopposed invasion
: having no opponent
a politician who is running for election unopposed
2
medical : being or relating to estrogen replacement therapy in which a progestin (such as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (such as endometrial cancer) associated with estrogen used alone
A woman who has had her uterus removed can take the estrogen "unopposed"—that is, without the addition of progestin.—Consumer Reports

Examples of unopposed in a Sentence

Recent Examples on the Web
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County Clerk Monica Gordon and Treasurer Maria Pappas are unopposed and were declared winners just after polls closed, while Sheriff Tom Dart ran unopposed in the primary and faces Libertarian Brad Sandefur. — A.d. Quig, Chicago Tribune, 4 Nov. 2026 Clark, who has been in the Georgia House of Representatives since 2019, is projected to have beaten Republican Air Force veteran Jonathan Chavez, who ran unopposed in the GOP primary earlier this year. — Dan Raby, CBS News, 4 Nov. 2026 Most local candidates ran unopposed, including judges, school board members and county commissioners. — Nick Sullivan, Charlotte Observer, 4 Nov. 2026 Rancho Cordova City Council 2nd District In the 2nd District, Planning Commissioner Elliott Stevenson ran unopposed for a City Council seat. — Jennah Pendleton, Sacbee.com, 4 Nov. 2026 See All Example Sentences for unopposed

Word History

First Known Use

1625, in the meaning defined at sense 1

Time Traveler
The first known use of unopposed was in 1625

Browse Nearby Words

Cite this Entry

“Unopposed.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/unopposed. Accessed 7 Nov. 2026.

Medical Definition

unopposed

adjective
: being or relating to estrogen replacement therapy in which a progestin (as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (as endometrial cancer) associated with estrogen used alone
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