1
: not opposed
an unopposed invasion
: having no opponent
a politician who is running for election unopposed
2
medical : being or relating to estrogen replacement therapy in which a progestin (such as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (such as endometrial cancer) associated with estrogen used alone
A woman who has had her uterus removed can take the estrogen "unopposed"—that is, without the addition of progestin.Consumer Reports

Examples of unopposed in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Parks ran unopposed in 2014, defeated fellow Republican Tad Schnaufer in 2018 with 72% of the vote, and won again in 2022 against write-in candidate Tommie Powers. James Wilkins, The Orlando Sentinel, 12 Aug. 2026 Jensen will face off against Zach Filipovich, who ran unopposed for the DFL nomination, in the general election. Wcco Staff, CBS News, 11 Aug. 2026 District 36 Incumbent candidate Lynn Melton, a Democrat who has served District 36 since 2023, ran unopposed in the primary. Sofi Zeman, Kansas City Star, 5 Aug. 2026 Those two unopposed re-elections were instead approved by acclamation, a process that installed Infantino for another four years without the need for a ballot. Philip Buckingham, New York Times, 4 Aug. 2026 See All Example Sentences for unopposed

Word History

First Known Use

1625, in the meaning defined at sense 1

Time Traveler
The first known use of unopposed was in 1625

Browse Nearby Words

Cite this Entry

“Unopposed.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/unopposed. Accessed 17 Aug. 2026.

Medical Definition

unopposed

adjective
: being or relating to estrogen replacement therapy in which a progestin (as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (as endometrial cancer) associated with estrogen used alone
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