1
2
: the base on which an organism lives
the soil is the substrate of most seed plants
3
: a substance acted upon (as by an enzyme)

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With its Latin prefix sub-, "below", substrate obviously refers to a layer under something else. Rock may serve as the substrate for the coral in a coral reef. Tiny wafers of silicon (or another semiconductor) serve as the substrate for computer chips. Substrate may also mean subsoil—that is, the layer under the topsoil, lacking in organic matter or humus. Substrate is part of the vocabulary of various other sciences, including chemistry and biology. But although it's mostly a scientific term, writers may also use it to mean simply "foundation"—for instance, when observing that reading is the substrate on which most other learning is based.

Examples of substrate in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Unlike the rigid glass surface of a standard smartphone, foldables use an OLED display mounted on a flexible plastic substrate and covered with ultra-thin glass (UTG) that's thinner than a human hair and capable of bending. Stephen J. Beard, USA Today, 9 Sep. 2026 Sensorial instincts are vital because water gilding—the application of a micro-thin layer of metal or other ornamental substrate to a surface—is an art form of more than 18 steps, some featuring processes going back 5,000 years. Clare Coulson, Condé Nast Traveler, 8 Sep. 2026 Researchers deposit and pattern optical waveguides, which act as tiny pathways for light, on a silicon substrate. Neetika Walter, Interesting Engineering, 3 Sep. 2026 Saturated in velvety blues, reds, and blacks, Zumthor’s surfaces all but vibrate; the subtle variations in the application of the paint and the alchemy of the pigment on the concrete substrate bring the walls maximally to life. Katy Barkan, Artforum, 1 Sep. 2026 See All Example Sentences for substrate

Word History

Etymology

Medieval Latin substratum

First Known Use

1730, in the meaning defined at sense 1

Time Traveler
The first known use of substrate was in 1730

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Cite this Entry

“Substrate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/substrate. Accessed 17 Sep. 2026.

Kids Definition

1
: an underlying layer: as
b
: the base on which an organism lives or over which it moves
the soil is the substrate of most plants
2
: a substance acted upon (as by an enzyme)

Medical Definition

1
2
: the base on which an organism lives
3
: a substance acted upon (as by an enzyme)
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