Knoevenagel reaction

noun Knoe·ve·na·gel reaction \ kəˈnə(r)vəˌnāgəl- , kəˈnə̄v- \
variants: or Knoevenagel condensation

Definition of Knoevenagel reaction

: an aldol-type condensation catalyzed by amines that takes place between an aldehyde or ketone and a compound containing an active methylene group (as in esters of acetoacetic acid, malonic acid, or cyanoacetic acid)

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Origin and Etymology of knoevenagel reaction

after Emil Knoevenagel †1921 German chemist


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