Knoevenagel reaction

Knoe·​ve·​na·​gel reaction | \ kəˈnə(r)vəˌnāgəl-, kəˈnə̄v- \
variants: or Knoevenagel condensation

Definition of Knoevenagel reaction

: an aldol-type condensation catalyzed by amines that takes place between an aldehyde or ketone and a compound containing an active methylene group (as in esters of acetoacetic acid, malonic acid, or cyanoacetic acid)

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History and Etymology for Knoevenagel reaction

after Emil Knoevenagel †1921 German chemist

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Cite this Entry

“Knoevenagel reaction.” Dictionary, Merriam-Webster, Accessed 12 Aug. 2020.

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