end-stage

adjective

ˈend-ˌstāj 

: being or occurring in the final stages of a terminal disease or condition

end-stage renal disease

Examples of end-stage in a Sentence

Recent Examples on the Web

While some people can clear the infection on their own, the majority are at major risk of developing chronic, potentially fatal conditions like cirrhosis and end-stage liver disease. — Philip A. Chan, STAT, 8 Oct. 2026

By the time symptoms appear, and the disease is diagnosed, many patients are approaching end-stage kidney disease. — Shiv Sudhakar, FOXNews.com, 15 Sep. 2026

In December 2023, Pacheco was diagnosed with end-stage renal disease. — Nicole Acevedo, NBC news, 31 July 2026

Nilsson battled end-stage kidney disease for more than four years and received dialysis three days a week, according to a family post on his Facebook page. — Melissa Ruggieri, USA Today, 3 July 2026

Word History

First Known Use

1920, in the meaning defined above

Rhymes for end-stage

• assuage
• backstage
• bocage
• downstage
• engage
• enrage
• leafage
• messuage
• offstage
• onstage
• outrage
• pelage

Medical Definition

end-stage

adjective

ˈend-ˌstāj 

: being or occurring in the final stages of a terminal disease or condition

end-stage liver failure