: being or occurring in the final stages of a terminal disease or condition
end-stage renal disease

Examples of end-stage in a Sentence

Recent Examples on the Web
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The feat could open the door to more transplants for people living with HIV who have end-stage organ disease. Tanya Lewis, Scientific American, 19 June 2026 Her son, Steve Cox, said the loss is especially painful because Zepeda had recently volunteered to donate one of her kidneys to him after he was diagnosed with end-stage renal disease. Steve Large, CBS News, 17 June 2026 The biological ventricular assist tissue in a patch, called BioVAT for short, was conceived as a bridge to either transplant, where wait times are long, or to implantation of a left ventricular assist device, or LVAD, in end-stage heart failure. Elizabeth Cooney, STAT, 27 May 2026 Troy was ultimately diagnosed with end-stage kidney disease due to hypertension. Erin Clack, PEOPLE, 16 May 2026 See All Example Sentences for end-stage

Word History

First Known Use

1920, in the meaning defined above

Time Traveler
The first known use of end-stage was in 1920

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Cite this Entry

“End-stage.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/end-stage. Accessed 30 Jun. 2026.

Medical Definition

end-stage

adjective
: being or occurring in the final stages of a terminal disease or condition
end-stage liver failure
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