: being or occurring in the final stages of a terminal disease or condition
end-stage renal disease

Examples of end-stage in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
But only the sickest of the sick are listed; just 1 in 8 patients with end-stage renal disease are on the waitlist. Nadia Kounang, CNN Money, 16 Jan. 2026 The hepatitis B virus causes more than a million deaths worldwide each year from end-stage liver failure, cirrhosis, and liver cancer. Emilie G.c. Thompson, STAT, 15 Jan. 2026 Robb Layne volunteered as a living organ donor to help Doris Pittell, who, at 79 years old, was diagnosed with end-stage kidney disease. Kelsie Hoffman, CBS News, 8 Dec. 2025 Despite the use of medications to treat dilated, weak hearts, some patients suffer from continued weakening of the heart muscle and progress to end-stage, or advanced, heart failure. William Cornwell, The Conversation, 19 Nov. 2025 See All Example Sentences for end-stage

Word History

First Known Use

1920, in the meaning defined above

Time Traveler
The first known use of end-stage was in 1920

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Cite this Entry

“End-stage.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/end-stage. Accessed 30 Jan. 2026.

Medical Definition

end-stage

adjective
: being or occurring in the final stages of a terminal disease or condition
end-stage liver failure
Last Updated: - Updated example sentences
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