bloodstream

noun

blood·​stream ˈbləd-ˌstrēm 

1

: the flowing blood in a circulatory system

2

: a mainstream of power or vitality

… introduce into the economic bloodstream a large amount of money …

—Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.

Recent Examples on the Web

Yogurt Yogurt is rich in probiotics that strengthen the gut lining and prevent inflammatory compounds from entering the bloodstream. — Christopher Bergland, Verywell Health, 12 Nov. 2026

Pike, 50, survived two doses of pentobarbital in September, which her attorneys say probably did not enter her bloodstream correctly and instead pooled in her arms, leaving them burned and blistered. — CBS News, 11 Nov. 2026

Peptides are typically administered through injections or nasal sprays as most break down in the human digestive tract before reaching the bloodstream. — Los Angeles Times, 11 Nov. 2026

The carbon dioxide bubbles in carbonated alcoholic beverages like Champagne can speed up the rate of alcohol absorption into your bloodstream. — Cheryl Fenton, Flow Space, 9 Nov. 2026

Word History

First Known Use

13th century, in the meaning defined at sense 1

Rhymes for bloodstream

• abeam
• airstream
• daydream
• downstream
• esteem
• extreme
• grapheme
• hakim
• hornbeam
• lexeme
• mainstream
• midstream

Kids Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a circulatory system