antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Like Napoleon’s France avant tout, the recent reversion to America First is antagonizing allies everywhere. S. C. M. Paine, Foreign Affairs, 19 Aug. 2025 Markel said that while he and his wife, Christy, have been antagonized by wheelie riders, his view of the subgroup has changed over time. Patrick Connolly, The Orlando Sentinel, 16 Aug. 2025 Boat captain Charlie Nunn told the outlet that the collision was a freak accident and was not caused by antagonizing the whale, adding that the woman is lucky she was not hurt. Hollie Silverman, MSNBC Newsweek, 3 Aug. 2025 So, part of our mission here is that there couldn't be a time in American history when there has been more divisiveness and antagonizing antagonism among different cultures, races, religions and walks of life. Steve Baltin, Forbes.com, 19 July 2025 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

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Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 27 Aug. 2025.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

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