Synonyms of trials

trials

noun

plural of trial

1

as in ordeals

a test of faith, patience, or strength

living with her insufferable relatives was a real trial

Synonyms & Similar Words

• ordeals
• fires
• gauntlets
• crucibles
• crosses
• tribulations
• baptisms of fire
• initiations
• misfortunes
• challenges
• hardships
• baptisms
• misadventures
• tragedies
• woes
• vicissitudes
• privations
• adversities
• mishaps
• griefs
• grievances
• rigors
• troubles
• asperities
• complications
• mischances
• inconveniences
• afflictions
• difficulties
• acid tests
• discomforts
• nuisances
• litmus tests
• annoyances

2

as in rehearsals

a private performance or session in preparation for a public appearance

ran another trial of the aerial performance before opening night

Synonyms & Similar Words

• rehearsals
• previews
• practices
• dry runs
• dress rehearsals
• exercises
• drills
• walk-throughs
• run-throughs

3

as in tests

a procedure or operation carried out to resolve an uncertainty

trials by medical researchers haven't determined whether the medication is safe or not

Synonyms & Similar Words

• tests
• experiments
• experimentations
• tries
• efforts
• essays
• ordeals
• exercises
• attempts
• workouts
• rehearsals
• tryouts
• practices
• dry runs
• crucibles
• trial and errors
• shakedowns

4

as in attempts

an effort to do or accomplish something

will rest and make another trial at climbing the mountain

Synonyms & Similar Words

• attempts
• tries
• goes
• endeavors
• stabs
• bids
• shots
• assays
• offers
• essays
• passes
• flings
• struggles
• cracks
• strivings
• undertakings
• whirls
• bashes
• throes
• whacks
• trial and errors

5

as in headaches

something that is a source of irritation

trying to have a coherent phone conversation with his senile father was always a trial

Synonyms & Similar Words

• headaches
• frustrations
• thorns
• worries
• nuisances
• problems
• inconveniences
• irritants
• annoyances
• hair shirts
• exasperations
• rubs
• vexations
• aggravations
• pests
• anxieties
• irks
• peeves
• insults
• bugbears
• tribulations
• ruffles
• discomforts
• hassles
• burdens
• troubles
• menaces
• botherations
• predicaments
• curses
• affronts
• offenders
• plagues
• pinpricks
• aggros
• bothers
• annoyers
• plights
• upsets
• offenses
• sores
• millstones
• crosses
• disturbers
• mischiefs
• fleabites
• albatross
• afflictions
• pet peeves
• harassers
• hang-ups
• pandora's boxes

Antonyms & Near Antonyms

• pleasures
• joys
• delights

Example Sentences

Recent Examples of trials

Merck and Moderna are studying the vaccine in several trials across other tumors, such as non-small cell lung cancer, bladder cancer and renal cell carcinoma. — Annika Kim Constantino, CNBC, 19 Aug. 2026

In Phase 2b trials, the treatment showed a 49% reduction of melanoma return after patients underwent surgery and a 59% reduction of metastasization of the cancer to distant organs. — Sony Salzman, ABC News, 19 Aug. 2026

All is well behind them the following morning, as trials for new additions to the team kicked off with many interested ladies attending the tryouts. — Rosy Cordero, Deadline, 19 Aug. 2026

Academic Medicine’s Place in the Process The path from a mere observation to a real change in patient care involves basic researchers, clinical investigators, academic health centers, regulatory bodies, and the patients who participate in trials. — Matthew Kayser, USA Today, 18 Aug. 2026

Show creator Quinn Shephard told Netflix’s Tudum that her love for Y2K teen movies and erotic thrillers like Carrie, Jennifer’s Body and Heavenly Creatures, as well as her fascination with the Salem witch trials, inspired her to write The Body. — Yamillah Hurtado, PEOPLE, 18 Aug. 2026

But Mangione’s defense lost arguments to exclude the gun and his writings from being used at the trials after both judges found the search of his backpack that produced that evidence was legal. — Hannah Rabinowitz, CNN Money, 12 Aug. 2026

Deal of the Week Swiss biotech Vaderis Therapeutics raised $152 million from Goldman Sachs Alternatives and TCGX, among others, to run late-stage trials on its potential therapy for a rare bleeding disorder. — Amy Feldman, Forbes.com, 12 Aug. 2026

The federal jail facility houses defendants awaiting criminal trials; adjacent is an immigration detention facility known as B-18. — Brittny Mejia, Los Angeles Times, 11 Aug. 2026