Synonyms of head-to-head

head-to-head

adverb

ˈhed-tə-ˈhed 

as in toe-to-toe

in direct confrontation or competition

it's fitting that the two best teams during the regular season will go head-to-head for the championship

Synonyms & Similar Words

• toe-to-toe
• one-on-one
• face-to-face
• head-on
• eyeball-to-eyeball
• mano a mano

Example Sentences

Recent Examples of head-to-head

Kristin gives up immediately, Cristain taps out shortly thereafter, and Sharonda loses out on the last spot to Kilby as the two try to choke down their dinner in a head-to-head battle. — Brian Moylan, Vulture, 5 Nov. 2026

If the decision was based on head-to-head matchups, Brantley would have clinched the final spot after blowing out Hagerty on Friday 56-0. — Chris Hays, The Orlando Sentinel, 5 Nov. 2026

Wake Forest is the only other team with one conference loss, and Miami has the head-to-head win over the Demon Deacons anyway. — Jordan McPherson, Miami Herald, 1 Nov. 2026

Now, both reptiles are going head-to-head, though each is retracted into the protection of its shell. — Margherita Bassi, Popular Science, 1 Nov. 2026

No head-to-head trials have yet compared remibrutinib with fenebrutinib or anti-CD20 treatments, making direct comparisons difficult. — Elsa Ohlen, CNBC, 30 Oct. 2026

The experimental diabetes and obesity drug retatrutide continues to show impressive results in clinical trials, with the latest study comparing the medication head-to-head with the GLP-1 medication Ozempic (semaglutide). — Tom Gavin, EverydayHealth.com, 28 Oct. 2026

Lilly’s triple-G drug beats Ozempic in head-to-head study Eli Lilly said this morning that its investigational drug retatrutide was more effective at lowering blood sugar and cutting weight than Novo Nordisk’s Ozempic in a large diabetes study. — Elaine Chen, STAT, 28 Oct. 2026

After Monday night’s 38-21 Cowboys win over the Eagles, Dallas (+115) moved back ahead of the Giants (+125) as the betting odds favorite to claim the division crown, even with New York owning its Week 1 head-to-head win against them. — Pat Leonard, New York Daily News, 27 Oct. 2026