How to Use polypeptide in a Sentence

polypeptide

noun
  • Almost all of the increase and almost all of the total was due to an increase in polypeptides, which are used to make insulin.
    Ken Roberts, Forbes.com, 29 May 2025
  • There are also polypeptide chains that are the sides of the ladder, connecting the rungs vertically.
    Kirbie Johnson, Allure, 8 Apr. 2022
  • That is seven more years those polypeptides would receive if they were approved under the rules for regular small-molecule drugs, such as pills.
    Jeff Stein, Washington Post, 20 Dec. 2019
  • This powerful polypeptide helps add hydration to your skin while also working to firm and diminish the appearance of fine lines and wrinkles.
    Savannah Smith, Rolling Stone, 1 July 2024
  • Repeats with a lot of proline, threonine and serine transform a typical protein to a mucin because of the polypeptide structure that is formed.
    Coren Walters-Stewart, Discover Magazine, 18 Oct. 2022
  • The polypeptides are even resistant to reheating, a major aspect in overall food production.
    Andrew Paul, Popular Science, 8 Oct. 2025
  • It is synthesized as part of two much longer polypeptides, the product of the initial long open reading frame (orf1a), and from the orf1b, the orf1ab polypeptide.
    William A. Haseltine, Forbes, 4 June 2021
  • It’s formulated with B-silk, a polypeptide designed to emulate strong spider silk, plus rice protein and panthenol to keep the lash line nourished and healthy.
    Genevieve Cepeda, InStyle, 6 Feb. 2026
  • Within a fraction of a second of its creation, a polypeptide string bends, buckles and folds precisely into the protein’s final three-dimensional shape.
    Quanta Magazine, 26 June 2024
  • Aviptadil is a synthetic form of human vasoactive intestinal polypeptide, which is highly concentrated in the lungs.
    Melissa Healystaff Writer, Los Angeles Times, 2 May 2020
  • But Mounjaro targets a second hormone, the glucose-dependent insulinotropic polypeptide, as well.
    Matthew Herper, STAT, 14 May 2022
  • The hero ingredient is vegan collagen and elastin polypeptides, plus two types of hyaluronic acid for major hydration and niacinamide for a healthy skin barrier.
    Celia Shatzman, Forbes, 26 Nov. 2024
  • After adding the polypeptides, the dessert could withstand temperatures as low as -4 degrees Fahrenheit before degrading.
    Andrew Paul, Popular Science, 8 Oct. 2025
  • The formula combines antioxidant-rich grape seed and sweet almond oils with polypeptides (long chains of amino acids that act as building blocks for collagen and elastin) to help boost skin’s elasticity and resilience.
    Jamie Ballard, Allure, 14 Nov. 2025
  • This implied an elementary kind of coding, a basis for the exchange of information between the RNA and the polypeptide.
    Quanta Magazine, 19 Dec. 2017
  • The researchers found success using soy protein isolate—which has an entirely different molecular composition from spider silk—due to the fact that all proteins are comprised of polypeptide chains.
    Daisy Hernandez, Popular Mechanics, 14 June 2021
  • Keep your lips moisturized with this ultra-hydrating, plumping, polypeptide treatment that increases the volume of lip contours, leaving the appearance of naturally full lips.
    Daisy Maldonado, SELF, 12 Aug. 2022
  • Once its polypeptide chain is assembled, a protein can fold into its structure within a thousandth of a second — a timescale that perplexed the molecular biologist Cyrus Levinthal.
    Quanta Magazine, 26 June 2024
  • For years, researchers have unsuccessfully tried to harness these polypeptides’ antifreezing properties, but directly extracting the compounds from fish is simply too costly and not scalable.
    Andrew Paul, Popular Science, 8 Oct. 2025
  • What’s missing from such previous complexity measures, Cronin said, is any sense of the history of the complex object — the measures don’t distinguish between an enzyme and a random polypeptide.
    Philip Ball, Quanta Magazine, 4 May 2023
  • Second, tirzepatide has also been shown to bind to receptors that are normally targeted by glucose-dependent insulinotropic polypeptide (GIP) hormones.
    William A. Haseltine, Forbes, 24 Jan. 2023
  • Through their online escapades, tweens have come across products like Drunk Elephant’s polypeptide cream and The Ordinary’s squalane serum that contain skin-firming retinol meant for older, wrinkle-fearing adults.
    Bysasha Rogelberg, Fortune, 29 June 2024
  • These polypeptides then fold into complex three-dimensional structures called proteins, driven by a combination of hydrophobic interactions, hydrogen bonds and electrostatic forces between atoms along the chain.
    Kj Dhaliwal, Forbes.com, 26 June 2026
  • This supplement powder is rich in immunoglobulin, lactoferrin, and proline-rich polypeptides (PRPs), all of which work together to support immune function and protect against infection.
    Amber Smith, Discover Magazine, 25 Apr. 2023
  • This drug differs from semaglutide by targeting receptors for the hormone gastric inhibitory polypeptide (GIP) in addition to GLP-1.
    Lori Youmshajekian, Scientific American, 8 Apr. 2026
  • In 2015, Krishnamurthy, Hud and their collaborators showed that trying to understand the origins of polypeptide synthesis by focusing only on amino acids, the building blocks of peptides, might be the wrong tack.
    Quanta Magazine, 16 Sep. 2019
  • This includes a peptide known as vasoactive intestinal polypeptide (VIP), which is understood to have Alzehimer’s-busting effects and is associated with the regulation of blood flow and glymphatic clearance.
    William A. Haseltine, Forbes, 29 Feb. 2024
  • Other forms of iron in iron supplements include heme iron polypeptides (HIP), carbonyl iron, iron amino-acid chelates, and polysaccharide-iron complexes (PIC), which have fewer gastrointestinal side effects when compared to the ferric and ferrous salts.
    Bestreviews, Mercury News, 4 Feb. 2026

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'polypeptide.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Last Updated: