How to Use polygenic in a Sentence

polygenic

adjective

• Clients then use those polygenic risk scores to pick which embryos to use to try to have a baby.
  — Rob Stein, NPR, 6 May 2026
• Researchers who work with polygenic risk scores are concerned about their use in this context.
  — Laura Hercher, Scientific American, 12 July 2021
• Even then, polygenic risk scores do not always provide answers.
  — Gina Kolata, New York Times, 30 May 2023
• Traits shaped by many genes, called polygenic traits, are still poorly understood in horses.
  — Rupendra Brahambhatt, Interesting Engineering, 31 Aug. 2025
• Those markers and the risk in the genetics become what’s called a person’s polygenic risk score.
  — Madeline Holcombe, CNN, 3 Apr. 2023
• Currently, polygenic risk scores aren’t routinely done in the health care setting.
  — Madeleine Streets, SELF, 13 June 2022
• This confirmed that obesity is highly polygenic, meaning more than a single gene plays some sort of role in the process.
  — New Atlas, 21 July 2025
• Back in the lab Back at Herasight, Schleede shows how polygenic risk scores are calculated.
  — Rob Stein, NPR, 6 May 2026
• This can be done by determining someone’s genetic risk score, also known as a polygenic risk score8.
  — Madeleine Streets, SELF, 13 June 2022
• Each individual gene involved in a polygenic trait may exert only a small influence on that trait.
  — Kermit Pattison, Scientific American, 20 May 2025
• The videos show how, using advanced machine learning, one company is offering polygenic risk scoring.
  — Phineas Rueckert, Longreads, 3 Mar. 2026
• For some physical traits, such as height or body mass index, polygenic scores are associated with a sizeable fraction of the variation.
  — Jessica Riskin, The New York Review of Books, 21 Apr. 2022
• For example, polygenic scores are commonly used in animal and plant breeding to improve the chances of having healthy and resilient livestock and crops.
  — Wired, 6 July 2022
• Another challenge will be developing polygenic scores that don’t increase health care disparities.
  — Jeanne Erdmann, Discover Magazine, 17 Apr. 2020
• Higher polygenic risk scores are associated with earlier onset of migraines and more frequent and severe attacks8.
  — Madeleine Streets, SELF, 13 June 2022
• But the clinical value of polygenic risk scores for even straightforward medical conditions like asthma and stroke remains highly dubious.
  — Arthur Caplan & James Tabery, Scientific American, 28 July 2025
• Imagine designing screening trials not for the general population but for people already flagged by genetics—those with high polygenic scores for breast or colon cancer.
  — Siddhartha Mukherjee, New Yorker, 16 June 2025
• Each person’s genetic risk for dementia was estimated using polygenic risk, which measures your risk of contracting common chronic diseases due to your genes.
  — L'oreal Thompson Payton, Fortune Well, 14 Mar. 2023
• Traditionally, scientists have believed that telomere length is either a polygenic trait, controlled by multiple genes, or is passed directly to the offspring through parental sperm and egg cells.
  — New Atlas, 2 Oct. 2025
• But chronic diseases, like heart disease, Alzheimer's disease, and nonalcoholic fatty liver disease, are polygenic, which means environment plays a much bigger role.
  — Lisa Drayer, CNN, 13 May 2021
• In a recent paper published in Nature Medicine, scientists found that polygenic risk scores in general didn’t perform as well in people with African ancestry.
  — Angus Chen, STAT, 30 June 2022
• The report also called for the Federal Trade Commission to look carefully at claims made by any company using polygenic scoring to pick embryos.
  — Laura Hercher, Scientific American, 12 July 2021
• From the dataset, the researchers were able to create what’s known as a polygenic risk score, which takes into account which genetic variants a person has that have been linked to a higher BMI in adulthood.
  — Kaitlin Sullivan, NBC news, 21 July 2025
• The computerized analysis produces polygenic risk scores using complex algorithms developed from years of genetic research on large databases.
  — Rob Stein, NPR, 6 May 2026
• From genomic studies, scientists have developed the polygenic index, or PGI, a way to score the likelihood of a wide range of genetic outcomes.
  — Kate Zernike, New York Times, 23 Mar. 2025
• In polygenic risk scoring, medical practitioners use deep-learning algorithms that promise to screen not only for genetic disorders, but also traits like intelligence and height.
  — Phineas Rueckert, Longreads, 3 Mar. 2026
• The polygenic score that could help predict academic performance aims to assess genetic markers related to educational attainment.
  — NBC News, 14 Oct. 2020
• Your chronotype, according to these findings, is a complex polygenic trait with a heritability estimated at around 50%, shaped by hundreds of small genetic effects acting in concert.
  — Scott Travers, Forbes.com, 18 May 2026
• In the past decade, detailed knowledge about the specific loci underlying polygenic traits has begun to emerge from genome-wide association studies (GWAS).
  — Razib Khan, Discover Magazine, 6 Aug. 2013
• Companies perform these screens with polygenic risk scoring, which makes use of genetic mutations identified from large scale population studies to be associated with a complex trait like intelligence.
  — Tania Fabo, MSNBC Newsweek, 6 Aug. 2025