: any of various amides (such as sulfanilamide) of a sulfonic acid
also : sulfa drug

Examples of sulfonamide in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The researchers examined which children had been given prescriptions for penicillin, penicillin with B-lactamase inhibitor, cephalosporin, sulfonamide or macrolide within the first six months of life. — Jacqueline Howard, CNN, 20 Dec. 2019 Any positive test results for sulfonamides could be the result of leftover antibiotics from that time or intentional misuse, Jonker said. — Rebekah Tuchscherer, USA TODAY, 26 June 2019 Other antibiotics found to raise the risk of miscarriage include most macrolides, quinolones, tetracyclines, sulfonamides and metronidazole. — Paul Sisson, sandiegouniontribune.com, 2 May 2017

Word History

Etymology

sulfonic + amide

First Known Use

1881, in the meaning defined above

Time Traveler
The first known use of sulfonamide was in 1881

Browse Nearby Words

Cite this Entry

“Sulfonamide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sulfonamide. Accessed 26 Sep. 2026.

Medical Definition

sulfonamide

noun
sul·​fon·​amide
: any of various amides (as sulfanilamide) of a sulfonic acid
also : sulfa drug

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