sulfamethoxazole

noun

sul·​fa·​meth·​ox·​a·​zole ˌsəl-fə-ˌme-ˈthäk-sə-ˌzōl 

: an antibacterial sulfonamide C₁₀H₁₁N₃O₃S used alone or in combination with trimethoprim (as in the treatment of urinary tract infections or acute otitis media)

Examples of sulfamethoxazole in a Sentence

Recent Examples on the Web

Cyclosporiasis is treated with the antibiotic trimethoprim-sulfamethoxazole (TMP-SMX), which is sold under the brand names Bactrim, Septra or Cotrim, according to the CDC. — Finch Walker, USA Today, 30 July 2026

Unlike many common stomach bugs that resolve on their own, severe or persistent Cyclospora infections typically require a prescription antibiotic, most often trimethoprim-sulfamethoxazole, to fully eliminate the parasite. — Khloe Quill, FOXNews.com, 29 July 2026

He was prescribed Bactrim, a sulfamethoxazole-trimethoprim antibiotic commonly used to treat Cyclosporiasis, and said his symptoms improved within several hours of taking the first pill. — Janelle Mella, Charlotte Observer, 21 July 2026

Usually, the first-choice treatment is trimethoprim/sulfamethoxazole, a sulfonamide antibiotic commonly referred to by the brand names Bactrim or Septra. — Elise Haulund, CNN Money, 18 July 2026

Word History

Etymology

sulfa + methyl + oxazole, a compound C₃H₃NO (from International Scientific Vocabulary ox- + azole)

First Known Use

1960, in the meaning defined above

Rhymes for sulfamethoxazole

• benzimidazole
• dipyridamole
• itraconazole
• ketoconazole
• metronidazole
• sulfathiazole
• thiabendazole
• acholi
• emboli
• sertoli
• unholy
• carbazole

Medical Definition

sulfamethoxazole

noun

sul·​fa·​meth·​ox·​a·​zole

variants or chiefly British sulphamethoxazole

-ˌmeth-ˈäk-sə-ˌzōl 

: an antibacterial sulfonamide C₁₀H₁₁N₃O₃S used alone (as in the treatment of urinary tract infections or prophylaxis against meningococcal meningitis) or in combination with trimethoprim (as in the treatment of Pneumocystis carinii pneumonia, shigellosis, acute otitis media, or urinary tract infections) see bactrim, septra