substance P

noun

: a neuropeptide that consists of 11 amino acid residues, that is present in the nervous system and gastrointestinal tract, that causes the contraction of smooth muscle and dilation of blood vessels, and that acts as a potent neurotransmitter especially in the transmission of signals from pain receptors

Examples of substance P in a Sentence

Recent Examples on the Web According to the American Migraine Foundation, magnesium decreases substance P and glutamate. Allison Futterman, Discover Magazine, 4 Apr. 2024

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'substance P.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1934, in the meaning defined above

Time Traveler
The first known use of substance P was in 1934

Dictionary Entries Near substance P

Cite this Entry

“Substance P.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/substance%20P. Accessed 24 Apr. 2024.

Medical Definition

substance P

noun
: a neuropeptide that consists of 11 amino acid residues, that is widely distributed in the brain, spinal cord, and peripheral nervous system, and that acts across nerve synapses to produce prolonged postsynaptic excitation

More from Merriam-Webster on substance P

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!