spi·​ro·​no·​lac·​tone ˌspī-rə-nō-ˈlak-ˌtōn How to pronounce spironolactone (audio) spi-ˌrō-nə- How to pronounce spironolactone (audio)
: an aldosterone antagonist C24H32O4S that promotes diuresis and sodium excretion and is used to treat essential hypertension, edema with congestive heart failure, hepatic cirrhosis with ascites, nephrotic syndrome, and idiopathic edema

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Cite this Entry

“Spironolactone.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/spironolactone. Accessed 28 Nov. 2023.

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