reuptake

noun

re·​up·​take (ˈ)rē-ˈəp-ˌtāk How to pronounce reuptake (audio)
: the reabsorption by a neuron of a neurotransmitter following the transmission of a nerve impulse across a synapse

Examples of reuptake in a Sentence

Recent Examples on the Web
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Other medication classes, such as serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants or tricyclic antidepressants, may also be used depending on individual needs. Daryl Austin, USA Today, 14 Mar. 2026 Specifically, Isaacson wonders about the long-term effects of her medication, a serotonin-norepinephrine reuptake inhibitor that is known to raise blood pressure. The New York Times News Service Syndicate, San Diego Union-Tribune, 27 Jan. 2026 Antidepressants Antidepressants, including selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs), increase serotonin levels in the brain to improve mood and behavior.9 Both ginseng and St John’s wort may increase serotonin levels. Jessica Swirble, Verywell Health, 5 Jan. 2026 Most were taking either a selective serotonin reuptake inhibitor (SSRI) or a serotonin and norepinephrine reuptake inhibitor (SNRI). Emily Kay Votruba, EverydayHealth.com, 11 Dec. 2025 See All Example Sentences for reuptake

Word History

First Known Use

1968, in the meaning defined above

Time Traveler
The first known use of reuptake was in 1968

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Cite this Entry

“Reuptake.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/reuptake. Accessed 12 May. 2026.

Medical Definition

reuptake

noun
re·​up·​take (ˈ)rē-ˈəp-ˌtāk How to pronounce reuptake (audio)
: the reabsorption by a neuron of a neurotransmitter following the transmission of a nerve impulse across a synapse
antidepressants which block the reuptake of norepinephrine
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