Medical Dictionary

prodrug

noun pro·drug \ ˈprō-ˌdrəg \

medical Definition of prodrug

: a pharmacologically inactive substance that is the modified form of a pharmacologically active drug to which it is converted (as by enzymatic action) in the body
  • One source of the variability is the metabolism of clopidogrel, which is a prodrug requiring biotransformation to generate its active metabolite.
  • —Jessica L. Mega et al.The Journal of the American Medical Association27 Oct. 2010

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