Medical Dictionary

prodrug

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noun pro·drug \ˈprō-ˌdrəg\

Medical Definition of prodrug

  1. :  a pharmacologically inactive substance that is the modified form of a pharmacologically active drug to which it is converted (as by enzymatic action) in the body One source of the variability is the metabolism of clopidogrel, which is a prodrug requiring biotransformation to generate its active metabolite.—Jessica L. Mega et al., The Journal of the American Medical Association, 27 Oct. 2010


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