osteogenesis imperfecta

noun

osteogenesis im·​per·​fec·​ta -ˌim-(ˌ)pər-ˈfek-tə 

: a hereditary disease caused by defective or deficient collagen production and marked by extreme brittleness of the long bones and a bluish color of the whites of the eyes

called also brittle bone disease, brittle bones

Examples of osteogenesis imperfecta in a Sentence

Recent Examples on the Web

Young, now 28, was born with what’s known as osteogenesis imperfecta, or brittle bone disease. — Nushrat Rahman, Freep.com, 16 Oct. 2025

Watson was born with osteogenesis imperfecta, or brittle bone disease, a genetic condition in which the body does not make enough collagen to keep bones strong. — Theresa Braine, Mercury News, 29 Dec. 2025

The actor also has osteogenesis imperfecta, a condition that causes fragile bones and lower-than-average height. — Will Harris, EW.com, 30 July 2025

That can be declared of Christopher Lynch, an awarding-winning Irish filmmaker based in London, who was born with osteogenesis imperfecta. — Shirl Leigh march 02, New Atlas, 2 Mar. 2026

Word History

Etymology

New Latin, imperfect osteogenesis

First Known Use

1899, in the meaning defined above

Rhymes for osteogenesis imperfecta

• analecta
• ejecta
• insecta
• recta

Medical Definition

osteogenesis imperfecta

noun

osteogenesis im·​per·​fec·​ta -ˌim-pər-ˈfek-tə 

: a hereditary disease caused by defective or deficient collagen production and marked by extreme brittleness of the long bones and a bluish color of the whites of the eyes

called also brittle bone disease, brittle bones, fragilitas ossium, osteopsathyrosis