metastasize

verb

me·​tas·​ta·​size mə-ˈta-stə-ˌsīz How to pronounce metastasize (audio)
metastasized; metastasizing

intransitive verb

: to spread or grow by or as if by metastasis
died of lung cancer which had metastasized throughout his bodyG. P. Elliott

Examples of metastasize in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Mellencamp was diagnosed with stage 4 cancer earlier this year, after her melanoma metastasized in her brain and lungs. Elizabeth Stanton , Larry Fink, FOXNews.com, 29 Apr. 2025 Fear of political caprice masquerading as strategy, of a trade war metastasizing into financial contagion, and of a world where traditional safe havens—currencies, institutions, alliances—no longer offer much safety at all. Mohammed Soliman, MSNBC Newsweek, 29 Apr. 2025 Trump’s Comments Raise Legal Alarms Domestically, the mechanisms of deportation or the state punishing its enemies are unlikely to stop with Venezuelans or advocates of a Palestinian state, since the mechanism of power is based on paranoia, with one threat metastasizing and expanding. Viet Thanh Nguyễn, Time, 28 Apr. 2025 As more cysts develop, the mass looks and acts like cancer, forming necrotic cavities and sometimes metastasizing to other organs, such as the lungs and brain. ArsTechnica, 23 Apr. 2025 See All Example Sentences for metastasize

Word History

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of metastasize was in 1907

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Cite this Entry

“Metastasize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/metastasize. Accessed 7 May. 2025.

Kids Definition

metastasize

verb
me·​tas·​ta·​size mə-ˈtas-tə-ˌsīz How to pronounce metastasize (audio)
: to spread or grow by or as if by metastasis

Medical Definition

metastasize

intransitive verb
me·​tas·​ta·​size
variants also British metastasise
metastasized also British metastasised; metastasizing also British metastasising
: to spread by metastasis
… all ten were primary brain cancers; that is, they had originated in the brain, and not metastasized there from elsewhere in the body.Paul Brodeur, The New Yorker
metastasization noun
also British metastasisation
Last Updated: - Updated example sentences
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