Medical Definition of leprechaunism
: a rare hereditary disorder of extreme insulin resistance that is characterized especially by intrauterine and postnatal growth retardation, skin abnormalities, hirsutism, emaciation, widely spaced eyes, thick lips, low-set ears, and enlarged genitalia and is usually fatal during early infancy : donohue syndrome
Note: This disorder is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene on a chromosome other than a sex chromosome.
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