lep·​re·​chaun·​ism ˈlep-rə-ˌkän-ˌiz-əm, -ˌkȯn- How to pronounce leprechaunism (audio)
: a rare hereditary disorder of extreme insulin resistance that is characterized especially by intrauterine and postnatal growth retardation, skin abnormalities, hirsutism, emaciation, widely spaced eyes, thick lips, low-set ears, and enlarged genitalia and is usually fatal during early infancy : donohue syndrome

Note: This disorder is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene on a chromosome other than a sex chromosome.

Dictionary Entries Near leprechaunism

Cite this Entry

“Leprechaunism.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/leprechaunism. Accessed 25 Mar. 2023.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

A Good Old-Fashioned Quiz

Name That Thing

You know what it looks like… but what is it called?

Solve today's spelling word game by finding as many words as you can with using just 7 letters. Longer words score more points.

Can you make 12 words with 7 letters?