isoleucine

noun

iso·​leu·​cine ˌī-sō-ˈlü-ˌsēn 

: a crystalline, hydrophobic, essential amino acid C₆H₁₃NO₂ that is obtained in its levorotatory l-form by the hydrolysis of dietary protein and is isomeric with leucine

Examples of isoleucine in a Sentence

Recent Examples on the Web

Higher intake of the amino acids methionine, isoleucine and valine may increase the risk of inflammation, obesity and other conditions associated with aging. — Vanessa Etienne, PEOPLE, 11 Nov. 2026

While some of these amino acids are chemically similar (like leucine and isoleucine), others have opposite charges. — ArsTechnica, 30 Sep. 2026

Researchers highlighted three essential amino acids that are building blocks of protein — methionine, isoleucine and valine. — Khloe Quill, FOXNews.com, 3 Aug. 2026

Three specific essential amino acids—leucine, isoleucine, and valine—are called Branched-Chain Amino Acids. — Shimite Obialo, Forbes.com, 26 May 2026

Word History

Etymology

International Scientific Vocabulary

First Known Use

1903, in the meaning defined above

Rhymes for isoleucine

• acetylene
• adamantine
• adenosine
• amphetamine
• anthropocene
• apoprotein
• aquamarine
• arsphenamine
• azobenzene
• buprenorphine
• catecholamine
• chlorobenzene

Medical Definition

isoleucine

noun

iso·​leu·​cine ˌī-sō-ˈlü-ˌsēn 

: a crystalline essential amino acid C₆H₁₃NO₂ isomeric with leucine

—abbreviation Ile