isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

 also  ˌi-

: the action of isolating : the condition of being isolated

Synonyms

• solitude
• privacy
• loneliness

Choose the Right Synonym for isolation

solitude, isolation, seclusion mean the state of one who is alone.

solitude may imply a condition of being apart from all human beings or of being cut off by wish or circumstances from one's usual associates.

a few quiet hours of solitude

isolation stresses detachment from others often involuntarily.

the isolation of the village in winter

seclusion suggests a shutting away or keeping apart from others often connoting deliberate withdrawal from the world or retirement to a quiet life.

lived in pastoral seclusion

Examples of isolation in a Sentence

the isolation of the mountain community

after the long book tour, the author looked forward to the isolation of his office

Recent Examples on the Web

This combination of isolation, altitude and temperature is what makes the site so scientifically valuable as a training ground for scientists and astronauts — and as a test site for equipment and rovers. —Rosanna Philpott, CNN Money, 24 Oct. 2025

Even in the 19th century, the novel was considered a dangerous medium, one that would trap people—especially impressionable young women—in the thrall of isolation and fantasy. —Ian Bogost, The Atlantic, 23 Oct. 2025

Despite the increasing isolation of Stalin’s Soviet Union from the rest of the world, Ioffe and his group were plugged into the international network of physicists throughout the 1920s and most of the 1930s. —Literary Hub, 23 Oct. 2025

Fear, like anxiety, often feeds on isolation, so the stronger your community, the better. —Sarah Durn, Popular Science, 23 Oct. 2025

Word History

First Known Use

1833, in the meaning defined above

Phrases Containing isolation

• in isolation
• reproductive isolation
• self-isolation

Rhymes for isolation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

 also  ˌis-ə-

1

: the act of isolating : the condition of being isolated

2

: separation of a population of living things from related forms in such a manner as to prevent crossbreeding

Medical Definition

isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

1

: the action of isolating or condition of being isolated

isolation of a virus

put the patient in isolation

2

: a segregation of a group of organisms from related forms in such a manner as to prevent crossing

3

: a psychological defense mechanism consisting of the separating of ideas or memories from the emotions connected with them