influenza

noun

in·​flu·​en·​za ˌin-(ˌ)flü-ˈen-zə 

1

a

: an acute, highly contagious, respiratory disease caused by any of three orthomyxoviruses:

(1)

or influenza A : moderate to severe influenza that in humans is marked especially by sudden onset, fever, sore throat, fatigue, muscle aches, inflammation of the respiratory mucous membranes, and cough, that has numerous variants caused by subtypes (such as H1N1, H2N2, or H3N2) of an orthomyxovirus (Alphainfluenzavirus influenzae) infecting humans and various animals (such as birds or pigs), and that may occur in seasonal epidemics or sometimes pandemics following mutation in the causative virus

(2)

or influenza B : influenza with less severe symptoms that is caused by an orthomyxovirus (Betainfluenzavirus influenzae) infecting only humans and especially children and that may occur in seasonal epidemics but not pandemics

(3)

or influenza C : mild influenza that is often asymptomatic, is caused by an orthomyxovirus (Gammainfluenzavirus influenzae) infecting only humans, and does not occur in epidemics or pandemics

b

: any of various human respiratory infections of undetermined cause

—not used technically

2

: any of various virus diseases of domestic animals marked especially by fever, respiratory symptoms, and inflammation of mucous membranes

Note: All types of influenza are commonly called "the flu."

influenzal

ˌin-(ˌ)flü-ˈen-zəl 

adjective

influenzal pneumonia

influenzal symptoms

Examples of influenza in a Sentence

Recent Examples on the Web

The risk for an influenza season dominated by H3N2 subclade K is moderate, available information from the agency suggests. —Michelle Del Rey, USA Today, 21 Nov. 2025

While not tied to the influenza virus, the symptoms can come on fast and fierce, with sufferers battling nausea, vomiting, diarrhea, fever, headache and body aches, all within 12 hours to two days after exposure. —Elaine Rojas-Castillo, CBS News, 20 Nov. 2025

At least 280 children died of influenza, the highest number since pediatric death numbers were required to be shared in 2004. —Brenda Goodman, CNN Money, 18 Nov. 2025

Minimal early data from public health laboratories nationwide show that about 63 percent of influenza A samples tested have been H3N2 and 37 percent have been H1N1, but the proportion that may be subclade K is not yet clear. —Emily Kay Votruba, EverydayHealth.com, 17 Nov. 2025

Word History

Etymology

Italian, literally, influence, from Medieval Latin influentia; from the belief that epidemics were due to the influence of the stars

First Known Use

1743, in the meaning defined at sense 1a

Phrases Containing influenza

• Asian influenza
• avian influenza
• swine influenza

Rhymes for influenza

• cadenza
• parainfluenza

Kids Definition

influenza

noun

in·​flu·​en·​za ˌin-(ˌ)flü-ˈen-zə 

1

: a very contagious virus disease with fever, exhaustion, severe aches and pains, and inflammation of the respiratory tract

2

: any of various diseases of human beings or domestic animals that are usually caused by viruses and are typically marked by fever and respiratory symptoms

Etymology

from Italian influenza, literally "influence," from Latin influentia "influence," derived from earlier influere "to flow in," from in- "in, into" and fluere "to flow"

Word Origin

Originally the Italian word influenza meant what the similar-sounding word in English, influence, means: "the act or power of producing an effect indirectly." But it also had the Latin meaning of "an invisible fluid through which the stars and planets control and direct the earth and things and people on it." When epidemics raged through Europe, no one knew what the real cause was. People blamed them on evil stars working through the invisible fluid, or influence. For this reason the Italians called the disease influenza. In 1743 an epidemic very much like our modern flu began in Rome and spread. That was when the Italian word was borrowed into English. Flu is a shortened form of influenza.

Medical Definition

influenza

noun

in·​flu·​en·​za ˌin-(ˌ)flü-ˈen-zə 

1

a

: an acute, highly contagious, respiratory disease caused by any of three orthomyxoviruses:

(1)

or influenza A : moderate to severe influenza that in humans is marked especially by sudden onset, fever, sore throat, fatigue, muscle aches, inflammation of the respiratory mucous membranes, and cough, is caused by any of several subtypes (such as H1N1, H2N2, or H3N2) of an orthomyxovirus (Alphainfluenzavirus influenzae) infecting humans and various animals (such as birds or pigs), and may occur in seasonal epidemics or sometimes pandemics following mutation of the causative virus see asian flu, avian influenza, bird flu, hong kong flu, spanish flu, swine flu, swine influenza

(2)

or influenza B : influenza with less severe symptoms that is caused by an orthomyxovirus (Betainfluenzavirus influenzae) infecting only humans and especially children and that may occur in seasonal epidemics but not pandemics

(3)

or influenza C : mild influenza that is often asymptomatic, is caused by an orthomyxovirus (Gammainfluenzavirus influenzae) infecting only humans, and does not occur in epidemics or pandemics

b

: any human respiratory infection of undetermined cause

—not used technically

2

: any of various viral diseases of domestic animals (such as shipping fever of horses) marked especially by fever, respiratory symptoms, and inflammation of mucous membranes

Note: All types of influenza are commonly called "the flu."

influenzal

-zəl 

adjective

influenzal pneumonia

influenzal symptoms