Medical Dictionary

Holmes–Adie syndrome

noun Holmes–Ad·ie syndrome \ˈhōmz-ˈā-dē-\

Medical Definition of Holmes–Adie syndrome

Biographical Note for holmes–adie syndrome

W. J. Adie

, —see adie's syndrome



Gordon Morgan

(1876–1965), British neurologist. Holmes is best remembered for his pioneering research on the cerebellum and the visual cortex. In 1906 he was appointed director of clinical research at London's National Hospital for Nervous Diseases. In 1908 he and another neurologist gave the first accurate account of the functions of the optic thalamus and its relation to the cerebral cortex. Working in a field hospital during World War I, he investigated the effects that lesions from specific areas of the brain had on vision, balance, and bladder function. On the staff of Charing Cross Hospital following the war, he was joined by the Australian neurologist William Adie. In 1941 they published separate papers on the syndrome that bears both their names. Holmes also investigated amyotonia congenita, and for many years he was editor of the medical journal Brain.

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